1372609-29-4

Upstream product

• 1187934-96-8 (3R)-7-(benzyloxy)-1-hepten-3-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 111-29-5 1 ,5-pentanediol 
• 4541-15-5 5-(benzyloxy)-1-pentanol 
• 78999-24-3 5-benzyloxy-1-pentanal 
• 100-39-0 benzyl bromide 
• 831171-32-5 7-(benzyloxy)hept-1-en-3-ol 

Downstream Products

• 1372609-30-7 (R)-5-(tert-butyldiphenylsilyloxy)hept-6-en-1-ol 
• 1373131-81-7 (R)-5-(tert-butyldiphenylsilyloxy)hept-6-enoic acid 
• 1372609-31-8 (R)-hept-1-en-4-yl (R)-5-(tert-butyldiphenylsilyloxy)hept-6-enoate 
• 1372609-33-0 (S)-hept-1-en-4-yl (R)-5-(tert-butyldiphenylsilyloxy)hept-6-enoate 
• 1372609-32-9 (6R,10R,E)-6-(tert-butyldiphenylsilyloxy)-10-propyl-3,4,5,6,9,10-hexahydro-2H-oxecin-2-one 
• 1372609-34-1 (6R,10S,E)-6-(tert-butyldiphenylsilyloxy)-10-propyl-3,4,5,6,9,10-hexahydro-2H-oxecin-2-one 

Relevant academic research and scientific papers

The first stereoselective total synthesis of putaminoxin e and its epimer and evaluation of their biological properties

Putaminoxin E, a natural nonanolide, and its C-9 epimer were synthesized for the first time starting from pentane-1,5-diol and butyraldehyde. The synthetic sequences involve Maruoka asymmetric allylation, Sharpless kinetic resolution, and ring-closing metathesis as the key steps. The cytotoxic and antimicrobial activities of these compounds were evaluated. Putaminoxin E, a natural nonanolide, and its C-9 epimer were synthesized for the first time starting from pentane-1,5-diol and butyraldehyde. Copyright