1372853-92-3Relevant academic research and scientific papers
Cu-Mn spinel oxide catalyzed synthesis of imidazo[1,2-a]pyridines through domino three-component coupling and 5-exo-dig cyclization in water
Bharate, Jaideep B.,Guru, Santosh K.,Jain, Shreyans K.,Meena, Samdarshi,Singh, Parvinder Pal,Bhushan, Shashi,Singh, Baldev,Bharate, Sandip B.,Vishwakarma, Ram A.
, p. 20869 - 20876 (2013)
An efficient and eco-friendly synthesis of therapeutically important and structurally diverse imidazo[1,2-a]pyridines using recyclable bimetallic Cu-Mn spinel oxide catalyst in aqueous medium has been developed. The Cu-Mn catalyzed domino three-component
Magnetic Cu0@HAP@γ-Fe2O3 nanoparticles: An efficient catalyst for one-pot three-component reaction for the synthesis of imidazo[1,2-a]pyridines
Sun, Wei,Jiang, Wei,Zhu, Gan,Li, Yiqun
, p. 91 - 100 (2018/09/05)
Cu(0) incorporated magnetic hydroxyapatite nanoparticles (Cu0@HAP@γ-Fe2O3 NPs) was conveniently synthesized via the ion exchange reaction, oxidation, and reduction steps. The structure and composition of the nanohybrid wer
Development of novel efficient 2D nanocomposite catalyst towards the three-component coupling reaction for the synthesis of imidazo[1,2-a]pyridines
Hussain, Najrul,Gogoi, Pranjal,Das, Manash R.,Sengupta, Pinaki,Fedorov, Vladimir E.,Asanov, Igor P.,Kozlova, Mariia N.,Artemkina, Sofya B.
, p. 368 - 379 (2017/06/19)
Two dimensional (2D) materials such as graphene and functionalized hexagonal boron nitride (h-BN) supported copper catalysts (CuO/rGO, CuO/h-BN, Cu(0)/rGO, Cu(0)/h-BN, CuS/rGO and CuS/h-BN) were prepared, characterized and evaluated their catalytic activity for the synthesis of imidazo[1,2-a]pyridines via one pot three component reaction between 2-aminopyridine, aldehyde and terminal alkynes. The imidazo[1,2-a]pyridines are an imperative class of nitrogen ring containing heterocyclic compounds which has wide range of applications in medicinal chemistry and drug molecule production. The reported synthetic protocol provides a rapid access to substituted imidazo[1,2-a]pyridines with excellent yields. CuO/rGO nanocomposite material was found to be highly active catalyst for the aforementioned reaction. The advantages of our protocol for the preparation of imidazo[1,2-a]pyridines over other previously reported includes shorter reaction times, functional group tolerance, recyclable catalyst and additive-free.
CuSO4-glucose for in situ generation of controlled Cu(I)-Cu(II) bicatalysts: Multicomponent reaction of heterocyclic azine and aldehyde with alkyne, and cycloisomerization toward synthesis of N-fused imidazoles
Guchhait, Sankar K.,Chandgude, Ajay L.,Priyadarshani, Garima
experimental part, p. 4438 - 4444 (2012/07/03)
The catalytic efficiency of mixed Cu(I)-Cu(II) system in situ generated by partial reduction of CuSO4 with glucose in ethanol (nonanhydrous) under open air has been explored. With this catalysis, the multicomponent cascade reaction of A3-coupling of heterocyclic amidine with aldehyde and alkyne, 5-exo-dig cycloisomerization, and prototropic shift has afforded an efficient and eco-friendly synthesis of therapeutically important versatile N-fused imidazoles. Diverse heterocyclic amidines, several of which are known to be poorly reactive, and aldehydes are compatible in this catalytic process.
