137314-76-2

Upstream product

• 6044-68-4 3,3-dimethoxyprop-1-ene 
• 137314-75-1 norefedrine α-chloropropionamide 
• 492-41-1 (1R,2S)-norephedrine 

Downstream Products

• 143060-07-5 (2R,3S,6S,7R,7aR)-3,6,7-Trimethyl-2-phenyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one 
• 143060-08-6 (2R,3S,6S,7S,7aR)-3,6,7-Trimethyl-2-phenyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one 
• 14212-54-5 (+)-(R,R)-β-methylstyrene oxide 
• 143060-04-2 (3R,4R)-1-Benzyl-3,4-dimethyl-pyrrolidine 
• 142955-03-1 (3R,4R)-1-Benzyl-1-((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-3,4-dimethyl-pyrrolidinium; bromide 
• 142955-02-0 (1R,2S)-2-((3R,4R)-3,4-Dimethyl-pyrrolidin-1-yl)-1-phenyl-propan-1-ol 
• 137314-91-1 (2R,3S,6R,7R,7aS)-3,6,7-Trimethyl-2-phenyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one 
• 137314-78-4 (2R,3S,6R,7R,7aS)-7-Iodomethyl-3,6-dimethyl-2-phenyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one 
• 137314-77-3 2-Iodo-1-((2S,4S,5R)-4-methyl-5-phenyl-2-vinyl-oxazolidin-3-yl)-propan-1-one 

Relevant academic research and scientific papers

Stereoselective Radical-Mediated Cyclization of Norephedrine Derived α-Iodoamides: Synthesis of Enantiopure Pyrrolidines and Transition State Modelling

Radical-mediated cyclization of norephedrine derived α-iodoamides 1 was found to be highly stereoselective ( 97:3) favouring diastereoisomer 2.Bicyclic lactams 2 were transformed in high yields into enantiomerically pure pyrrolidines 10.Transition stat

Stereoselective Radical-Mediated Cyclization of Norephedrine Derived α-Iodoamides: Experiments and TS-Modelling

Radical-mediated cyclization of norephedrine derived α-iodoamides 1 was found to be highly stereoselective (97:3) favouring diastereoisomer 2.Transition state modelling with a force field developed ad hoc, nicely predicts the stereochemical results.