1373318-84-3

Basic information

• Product Name: Boceprevir Metabolite M4-d9
• Synonyms: Boceprevir Metabolite M4-d9;(1R,2S,5S)-3-[(2S)-2-[[[[1,1-(DiMethylethyl-d9)]aMino]carbonyl]aMino]-3,3-diMethyl-1-oxobutyl]-6,6-diMethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid
• CAS NO: 1373318-84-3
• Molecular Formula: C₁₉H₃₃N₃O₄
• Molecular Weight: 367.48302
• Product Categories: Amines;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Metabolites & Impurities;Pharmaceuticals
• Mol File: 1373318-84-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Boceprevir Metabolite M4-d9(CAS DataBase Reference)
• NIST Chemistry Reference: Boceprevir Metabolite M4-d9(1373318-84-3)
• EPA Substance Registry System: Boceprevir Metabolite M4-d9(1373318-84-3)

Safety Data

• Hazardous Substances Data: 1373318-84-3(Hazardous Substances Data)

Usage

Uses

A labelled metabolite of the Hepatitis C virus NS3 serine protease inhibitor Boceprevir (B675500).

Upstream product

• 1373318-83-2 C₂₀H₂₆⁽²⁾H₉N₃O₄ 

Downstream Products

• 1256751-11-7 [D₉]boceprevir 

Relevant articles and documents

Synthesis of [14C]boceprevir, [13C 3]boceprevir, and [D9]boceprevir, a hepatitis C virus protease inhibitor

Boceprevir is a hepatitis C virus (HCV) NS3 protease inhibitor for HCV treatment. [14C]Boceprevir (SCH 503034, trade name Victrelis) was synthesized from K14CN in 11 steps with an overall yield of 16.4%. [13C3]Boceprevir was synthesized in 16 steps with a 2.5% overall yield. The carbon-13 in the molecule was distributed along the peptide chain. [D9]Boceprevir was synthesized from [D9]-t- butylamine in four steps with an overall yield of 69%. Copyright 2012 John Wiley & Sons, Ltd. Boceprevir is an HCV NS3 protease inhibitor for HCV treatment. [14C]Boceprevir (SCH 503034, trade name Victrelis) was synthesized from K14CN in 11 steps with an overall yield of 16.4%. [13C3] Boceprevir was synthesized in 16 steps with a 2.5% overall yield. The carbon-13 in the molecule was distributed along the peptide chain. [D9]Boceprevir was synthesized from [D9]-t-butylamine in 4 steps with an overall yield of 69%.