1373344-31-0

Upstream product

• 67-56-1 methanol 
• 1373344-44-5 (1S,2R)-2-(2-carboxyethyl)-2-methyl-3-oxocyclohexyl benzoate 
• 878-47-7 (4aS,5S)-4,4a,5,6,7,8-hexahydro-5-hydroxy-4a-methylnaphthalen-2(3H)-one 
• 20007-99-2 Wieland-Miescher ketone 
• 32042-79-8 (+)-(4aS,5S)-5-benzoyloxy-4,4a,5,6,7,8-hexahydro-4a-methylnaphthalen-2(3H)-one 
• 98-88-4 benzoyl chloride 

Downstream Products

• 1373344-33-2 (2S,4aR,8aS)-2-hydroxy-4a-methyloctahydrochromen-5-N'-(2,4,6-triisopropylbenzenesulfono)hydrazone 
• 1373344-34-3 (2R,4aR,8aS)-4a-methyl-2-trityloxyoctahydrochromen-5-N'-(2,4,6-triisopropylbenzenesulfono)hydrazone 
• 1373344-32-1 (1S,2R)-2-(2-methoxycarbonylethyl)-2-methyl-3-benzoylcyclohexyl-N'-(2,4,6-triisopropylbenzenesulfono)hydrazone 

Relevant academic research and scientific papers

Enantioselective synthesis of a taxol C ring

An enantioselective synthesis of a C ring of taxol has been accomplished. The key step is an oxidative cleavage of a derivative of the Wieland-Miescher ketone. A first attempt of a Shapiro reaction modelling the coupling of the C ring with the A fragment of taxol was also successful.