1373497-83-6Relevant academic research and scientific papers
Simple synthesis of β-trifluoromethylstyrenes using (E)-trimethyl-(3,3,3-trifluoroprop-1-enyl)silane
Omote, Masaaki,Tanaka, Miyuu,Ikeda, Akari,Nomura, Shiho,Tarui, Atsushi,Sato, Kazuyuki,Ando, Akira
, p. 2286 - 2289 (2012)
(E)-Trimethyl-(3,3,3-trifluoroprop-1-enyl)silane (1) was synthesized as a reagent for use in Hiyama cross-coupling reactions for the production of β-trifluoromethylstyrene derivatives. Cross-coupling of 1 with electronically diverse aryl iodides was achieved by treatment with CsF in the presence of catalytic amounts of palladium to afford the desired products in moderate to good yields.
