1373543-38-4

Basic information

• Product Name: ethyl (2R,3S)-2,3-dihydroxy-3-[4-(methylsulfonyl)phenyl]propanoate
• Synonyms: ethyl (2R,3S)-2,3-dihydroxy-3-[4-(methylsulfonyl)phenyl]propanoate
• CAS NO: 1373543-38-4
• Molecular Weight: 288.321
• Mol File: 1373543-38-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl (2R,3S)-2,3-dihydroxy-3-[4-(methylsulfonyl)phenyl]propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2R,3S)-2,3-dihydroxy-3-[4-(methylsulfonyl)phenyl]propanoate(1373543-38-4)
• EPA Substance Registry System: ethyl (2R,3S)-2,3-dihydroxy-3-[4-(methylsulfonyl)phenyl]propanoate(1373543-38-4)

Safety Data

• Hazardous Substances Data: 1373543-38-4(Hazardous Substances Data)

Upstream product

• 5398-77-6 para-methanesulfonylbenzaldehyde 
• 5345-30-2 3-(4-methanesulfonyl-phenyl)-acrylic acid 
• 137473-27-9 ethyl (2E)-3-[4-(methylsulfonyl)phenyl]acrylate 

Downstream Products

• 1373543-40-8 ethyl (2R,3S)-3-hydroxy-3-[4-(methylsulfonyl)phenyl]-2-{[(4-nitrophenyl)sulfonyl]oxy}propanoate 

Relevant articles and documents

An efficient enantioselective synthesis of florfenicol based on sharpless asymmetric dihydroxylation

An efficient and highly enantioselective synthesis of florfenicol- via a new intermediate threo-dihydroxy ester, with a Sharpless asymmetric dihydroxylation as the key step, is reported. A ring-opening/reduction strategy avoids the formation of a chlorinated byproduct that occurs in Schumachers phenyloxazoline procedure. The overall yield of florfenicol by this new process is 23% based on 4-(methylsulfonyl)benzaldehyde. Georg Thieme Verlag Stuttgart · New York.