1373545-76-6

Basic information

• Product Name: N-[3-(4,4,6-trimethyl-1,2,3,4-tetrahydro-quinolin-2-yl)-phenyl]-methanesulfonamide
• Synonyms: N-[3-(4,4,6-trimethyl-1,2,3,4-tetrahydro-quinolin-2-yl)-phenyl]-methanesulfonamide
• CAS NO: 1373545-76-6
• Molecular Weight: 344.478
• Mol File: 1373545-76-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[3-(4,4,6-trimethyl-1,2,3,4-tetrahydro-quinolin-2-yl)-phenyl]-methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-(4,4,6-trimethyl-1,2,3,4-tetrahydro-quinolin-2-yl)-phenyl]-methanesulfonamide(1373545-76-6)
• EPA Substance Registry System: N-[3-(4,4,6-trimethyl-1,2,3,4-tetrahydro-quinolin-2-yl)-phenyl]-methanesulfonamide(1373545-76-6)

Safety Data

• Hazardous Substances Data: 1373545-76-6(Hazardous Substances Data)

Upstream product

• 1373546-95-2 4,4,6-trimethyl-2-(3-nitro-phenyl)-1,2,3,4-tetrahydro-quinoline 
• 17064-95-8 (E)-4-methyl-N-(3-nitrobenzylidene)aniline 
• 106-49-0 p-toluidine 
• 1373546-97-4 3-(4,4,6-trimethyl-1,2,3,4-tetrahydro-quinolin-2-yl)-phenylamine 
• 124-63-0 methanesulfonyl chloride 
• 99-61-6 3-nitro-benzaldehyde 

Relevant articles and documents

NOVEL TETRAHYDROQUINOLINE DERIVATIVES

The present invention relates to compounds according to formula (I) and pharmaceutically acceptable salts or esters thereof, wherein R1 to R7 have the significance given herein. The compounds are activators of AMP-activated protein kinase (AMPK) and are useful in the treatment or prophylaxis of diseases that are related to AMPK regulation, such as obesity, dyslipidemia, hyperglycemia, type 1 or type 2 diabetes and cancers.