1373752-23-8Relevant academic research and scientific papers
An axial-to-axial chirality transfer strategy for atroposelective construction of C–N axial chirality
Chen, Jiangwei,Cheng, Hong-Gang,Hong, Xin,Hua, Yu,Liu, Ze-Shui,Ma, Yuanyuan,Wu, Chenggui,Xie, Pei-Pei,Zhou, Qianghui
supporting information, p. 1917 - 1932 (2021/05/31)
C–N axially chiral skeletons are ubiquitous in bioactive natural products, pharmaceuticals, and chiral ligands. However, their atroposelective synthesis remains a formidable challenge because of their innate low configurational stability compared with tha
Rh2(II)-catalyzed intramolecular aliphatic C-H bond amination reactions using aryl azides as the N-atom source
Nguyen, Quyen,Sun, Ke,Driver, Tom G.
, p. 7262 - 7265 (2012/06/16)
Rhodium(II) dicarboxylate complexes were discovered to catalyze the intramolecular amination of unactivated primary, secondary, or tertiary aliphatic C-H bonds using aryl azides as the N-atom precursor. While a strong electron-withdrawing group on the nitrogen atom is typically required to achieve this reaction, we found that both electron-rich and electron-poor aryl azides are efficient sources for the metal nitrene reactive intermediate.
