1373763-27-9Relevant academic research and scientific papers
The influence of the polymerization approach on the catalytic performance of novel porous poly (ionic liquid)s for green synthesis of pharmaceutical spiro-4-thiazolidinones
Elyasi, Zahra,Monfared, Mohammad Reza Zand,Najafi, Gholam Reza,Safaei Ghomi, Javad
, p. 44159 - 44170 (2020/12/25)
Although poly (ionic liquids) (PILs) have attracted great research interest owing to their various applications, the performance of nanoporous PILs has been rarely developed in the catalysis field. To this end, a micro-mesoporous PIL with acid-base bifunc
Br?nsted acidic ionic liquids: Green, efficient and reusable catalyst for synthesis of fluorinated spiro [indole-thiazinones/thiazolidinones] as antihistamic agents
Arya, Kapil,Rawat, Diwan Singh,Dandia, Anshu,Sasai, Hiroaki
experimental part, p. 117 - 122 (2012/05/20)
Br?nsted acidic ionic liquid containing nitrogen-based organic cations 1-methylimidazolium and 1-butyl-3-methylimidazolium and inorganic anions such as BF4-, PF6- and PTSA - used as catalysts and reaction medium for synthesis of fluorinated spiro[3H-indole-3,2′-tetrahydro-1,3-thiazine]-2,4′(1H)-diones (4a-f), fluorinated spiro[3H-indole-3,2′-thiazolidine]-2,4′ (1H)-diones (5a-f) in 90-97% yield by one-pot environmentally benign microwave induced technique. Synthesized compounds have been evaluated for their ability to inhibit the contractions induced by histamine on guinea pig ileum. The measurement of pA2 values suggested that the reported compounds showed H1-antagonism.
"On water" synthesis of spiro-indoles via Schiff bases
Panda, Siva S.,Jain, Subhash C.
experimental part, p. 1187 - 1194 (2012/09/25)
A fast, efficient, and clean "on water" synthesis of new Schiff bases and their conversion to spiro compounds under microwave irradiation, as well as in water, is reported. Indol-2,3-diones were reacted separately with various heterocyclic and aromatic am
