137384-57-7

Upstream product

• 92126-30-2 3-phenyl-4,5-bis(hydroxymethyl)isoxazole 
• 7710-44-3 dimethyl 3-phenylisoxazole-4,5-dicarboxylate 

Downstream Products

• 137384-58-8 4,5-Dimethylene-3-phenyl-4,5-dihydro-isoxazole 
• 137384-60-2 3-Phenyl-4,7-dihydro-isoxazolo[4,5-d]pyridazine-5,6-dicarboxylic acid diethyl ester 
• 137384-59-9 3,6-Diphenyl-4,4a,7a,8-tetrahydro-isoxazolo[4,5-f]isoindole-5,7-dione 
• 143950-64-5 3,3-bis(2,6-dichlorophenyl)-3'-phenyl-isoxazole-5(4H)-spiro-5'-isoxazole-4'-spiro-5(4H)-isoxazole 
• 143950-63-4 3,3-bis(2,4,6-trimethylphenyl)-3'-phenyl-isoxazole-5(4H)-spiro-5'-isoxazole-4'-spiro-5-(4H)-isoxazole 

Relevant academic research and scientific papers

The isoxazole analogue of ortho-quinodimethane: Generation and cycloaddition reactions

4,5-Dihydro-4,5-dimethylene-3-phenyl-isoxazole (the isoxazole analogue of ortho-quinodimethane) has been generated in situ from 4,5-bis(bromomethyl)-3-phenyl-isoxazole by sodium iodide induced 1,4-elimination process and trapped with symmetrical and unsymmetrical dienophiles.

Spiroheterocycles from reaction of nitrile oxides with heterocyclic o-quinodimethanes

1,3-Dipolar cycloaddition to o-quinodimethanes has been observed for the first time in the reaction of pyrazole and isoxazole o-quinodimethanes 4-6 with the stable nitrile oxides 7 and 8. The products, dispiroisoxazolines 9-14, were isolated in moderate y