1373956-78-5

Basic information

• Product Name: 4-(2-hydroxybenzylidene)-2-methyl-1-(pyridin-4-ylmethyl)-1H-imidazol-5(4H)-one
• Synonyms: 4-(2-hydroxybenzylidene)-2-methyl-1-(pyridin-4-ylmethyl)-1H-imidazol-5(4H)-one
• CAS NO: 1373956-78-5
• Molecular Weight: 293.325
• Mol File: 1373956-78-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(2-hydroxybenzylidene)-2-methyl-1-(pyridin-4-ylmethyl)-1H-imidazol-5(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-hydroxybenzylidene)-2-methyl-1-(pyridin-4-ylmethyl)-1H-imidazol-5(4H)-one(1373956-78-5)
• EPA Substance Registry System: 4-(2-hydroxybenzylidene)-2-methyl-1-(pyridin-4-ylmethyl)-1H-imidazol-5(4H)-one(1373956-78-5)

Safety Data

• Hazardous Substances Data: 1373956-78-5(Hazardous Substances Data)

Upstream product

• 3731-53-1 4-(aminomethyl)pyridine 
• 137401-66-2 N-2-hydroxyphenylmethylene-2-methyl-5-4H-oxazoline 

Relevant articles and documents

Synthesis, biological activity and docking study of imidazol-5-one as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

A novel series of substituted imidazol-5-ones were designed, synthesized and evaluated for in vitro reverse transcriptase (RT) inhibition activity using reverse transcriptase assay kit (Roche, Colorimetric). It has been observed from in vitro screening that newly synthesized compounds possess RT inhibitory activity. Docking study was performed to study the binding orientation and affinity of synthesized compounds for RT enzyme.