13740-67-5

Usage

Uses

Used in Pharmaceutical Industry:
2,2-diphenyl-2,3-dihydro-1H-inden-1-one is used as a key intermediate in the synthesis of various pharmaceuticals. Its chemical structure allows it to be a building block for the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Perfumery Industry:
In the perfumery industry, 2,2-diphenyl-2,3-dihydro-1H-inden-1-one is utilized as a fragrance ingredient. Its sweet, floral scent makes it a valuable component in creating unique and pleasant aromas for perfumes and other fragranced products.
Used in Organic Synthesis:
2,2-diphenyl-2,3-dihydro-1H-inden-1-one serves as a versatile reagent in organic synthesis. Its chemical properties enable it to be used in the preparation of a wide range of organic compounds, including dyes, agrochemicals, and other specialty chemicals.
Used as a Fluorescence Reagent:
2,2-diphenyl-2,3-dihydro-1H-inden-1-one has demonstrated potential as a fluorescence reagent for the detection of metal ions. Its ability to emit light upon interaction with certain metal ions makes it a valuable tool in analytical chemistry and environmental monitoring.
Safety and Toxicity:
2,2-diphenyl-2,3-dihydro-1H-inden-1-one is considered to be of low toxicity, making it generally safe for use in various chemical applications. This characteristic is particularly important in industries such as pharmaceuticals and perfumery, where safety and minimal side effects are paramount.

Upstream product

• 66003-76-7 Diphenyliodonium triflate 
• 83-33-0 inden-1-one 
• 776-74-9 Bromodiphenylmethane 
• 62937-77-3 2,2-dimethoxyindan-1-one 
• 71-43-2 benzene 
• 16214-27-0 indan-1,2-dione 
• 40400-13-3 2-Iodobenzyl bromide 
• 86-29-3 Diphenylacetonitrile 
• 156-06-9 2-oxo-3-(phenyl)propionic acid 
• 856073-40-0 2,2,3-triphenyl-propionyl chloride 

Downstream Products

• 5324-00-5 2,3-diphenyl-1H-indene 
• 22256-19-5 cis-1,2-diphenylindan 
• 874532-10-2 methyl-(1,2,2-triphenyl-indan-1-yl)-ether 
• 39253-55-9 2,3,3-triphenyl-indan-1-one 
• 39253-56-0 1,1,2-Triphenyl-indan 
• 872786-15-7 1,1,2-triphenyl-1H-indene 
• 18636-54-9 1,2-diphenyl-1H-indene 
• 144712-12-9 1,2,2-Triphenyl-indan-1-ol 

Relevant academic research and scientific papers

PCP-Bis(phosphinite) pincer complexes: new homogeneous catalysts for α-arylation of ketones

Two new p-alkoxycarbonylated palladium bis(phosphinite) PCP pincer complexes are easily prepared and for the first time evaluated as homogeneous catalysts in α-arylation of ketone enolates. Apart from the total absence of phenyl-aryl exchange by-products and significantly low catalyst loadings, the general α-arylation protocols described in this letter feature not only a broad applicability to a range of ketones and aryl bromides with marked electronic and steric differences but also the possibility to generate mono-diarylated products.

Superacid-promoted hydroxyalkylation of 1,2-indandiones

1,2-Indandione reacts efficiently with arenes to give 2,2-diaryl-1- indanones by the hydroxyalkylation reaction. The Bronsted superacid CF3SO3H (triflic acid) is an effective catalyst for these condensation reactions. The requisite 1

Carbopalladation of nitriles: Synthesis of benzocyclic ketones and cyclopentenones via Pd-catalyzed cyclization of ω-(2-iodoaryl)alkanenitriles and related compounds

An efficient procedure for the synthesis of 2,2-disubstituted benzocyclic ketones by intramolecular carbopalladation of nitriles has been developed. The cyclization of substituted 3-(2-iodoaryl)-propanenitriles affords indanones in high yields. The reaction is compatible with a wide variety of functional groups. This methodology has been extended to the synthesis of tetralones and cyclopentenones.

Synthesis of benzocyclic ketones via palladium-catalyzed cyclization of ω-(2-iodoaryl)alkanenitriles

An efficient procedure for the synthesis of 2,2-disubstituted benzocyclic ketones by intramolecular carbopalladation of nitriles has been developed. The cyclization of substituted 3-(2-iodoaryl)propanenitriles affords indanones in high yields. The reactio

Direct α-arylation of ketones: The reaction of cyclic ketone enolates with diphenyliodonium triflate

Diphenyliodonium triflate 1a reacts with the lithium enolates of cyclic ketones 2 (ring size = 5 - 8), in the presence of stoichiometric quantities of copper cyanide, to afford the corresponding α-phenylated ketones 3 or α,α'-diphenylated ketones 4.