137401-52-6Relevant academic research and scientific papers
Copper(II)-Promoted Cyclization/Difunctionalization of Allenols and Allenylsulfonamides: Synthesis of Heterocycle-Functionalized Vinyl Carboxylate Esters
Casavant, Barbara J.,Khoder, Zainab M.,Berhane, Ilyas A.,Chemler, Sherry R.
, p. 5958 - 5961 (2016/01/09)
A unique method to affect intramolecular aminooxygenation and dioxygenation of allenols and allenylsulfonamides is described. These operationally simple reactions occur under neutral or basic conditions where copper(II) carboxylates serve as reaction promoter, oxidant, and carboxylate source. Moderate to high yields of heterocycle-functionalized vinyl carboxylate esters are formed with moderate to high levels of diastereoselectivity. Such vinyl carboxylate esters could serve as precursors to α-amino and α-oxy ketones and derivatives thereof.
Diastereoselective synthesis of pyrrolidine derivatives via a one-pot nitro-Mannich/hydroamination cascade using base and gold catalysis
?uri?, Andrej,Barber, David M.,Sanganee, Hitesh J.,Dixon, Darren J.
supporting information, p. 2777 - 2779 (2013/04/23)
An efficient one-pot nitro-Mannich/hydroamination cascade reaction for the synthesis of substituted pyrrolidines bearing three stereocentres is reported. Proceeding under the control of a combination of base and gold(i) catalysts, the cascade reaction aff
Stereoselectivity in Electrophile-Mediated Cyclisations. AgI-Catalysed Synthesis of Disubstituted Pyrrolidines; Crystal Structure of cis-5-Phenyl-N-tosylpyrrolidin-2-ylmethyl 4-Bromobenzoate
Gallagher, Timothy,Jones, Stephen W.,Mahon, Mary F.,Molloy, Kieran C.
, p. 2193 - 2198 (2007/10/02)
A series of phenyl-substituted allenic sulphonamides 5, 6 and 7 have been prepared and shown to undergo AgI-catalysed cyclisation to give the corresponding 2,5-, 2,4- and 2,3-disubstituted N-sulphonylpyrrolidines 8, 9, and 10 respectively.The i
