1374027-63-0Relevant academic research and scientific papers
Amines based on electron-rich fluoroaromatic hydrocarbons, and preparation method of amines
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Paragraph 0060-0063, (2019/10/15)
The invention provides amines based on electron-rich fluoroaromatic hydrocarbons, and a preparation method of the amines. The structure of the amines is as shown in a formula I. The invention also provides the preparation method of the amines based on the
Synthesis of some n-aryl α-Amino acids using diaryliodonium salts
Mckerrow, Jason D.,Al-Rawi, Jasim M.,Brooks, Peter
, p. 1227 - 1236 (2012/09/22)
Bis[(3'-methoxycarbonyl)phenyl]iodonium bromide (4a), bis (4'-methoxyphenyl)iodonium iodide (4b) and bis (4'-acetamidophenyl)iodonium iodide (4c) were employed for the first time in the arylation of α-amino acid methyl esters. Yields of the synthesised products 5, 6 and 7 were good to high. These were then hydrolyzed to the corresponding N-aryl α-amino acids 8 and 9. The chiral integrity of the amino acids was maintained throughout the reaction sequence as confirmed by the synthesis of chiral tripeptide 10 and dipeptides 11. The structures of the new compounds were confirmed by IR, 1H and 13C NMR in addition to CHN microanalysis or high resolution mass spectrometry.
