1374241-38-9

Basic information

• Product Name: methyl (1S,2R)-1-nitro-2-(3-methoxyphenyl)-cyclopropanecarboxylate
• Synonyms: methyl (1S,2R)-1-nitro-2-(3-methoxyphenyl)-cyclopropanecarboxylate
• CAS NO: 1374241-38-9
• Molecular Weight: 251.239
• Mol File: 1374241-38-9.mol

Chemical Properties

• CAS DataBase Reference: methyl (1S,2R)-1-nitro-2-(3-methoxyphenyl)-cyclopropanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (1S,2R)-1-nitro-2-(3-methoxyphenyl)-cyclopropanecarboxylate(1374241-38-9)
• EPA Substance Registry System: methyl (1S,2R)-1-nitro-2-(3-methoxyphenyl)-cyclopropanecarboxylate(1374241-38-9)

Safety Data

• Hazardous Substances Data: 1374241-38-9(Hazardous Substances Data)

Upstream product

• 626-20-0 3-methoxystyrene 
• 2483-57-0 methyl 2-nitroacetate 

Relevant articles and documents

Catalytic asymmetric synthesis of nitrocyclopropane carboxylates

A Cu(I)-catalyzed asymmetric cyclopropanation of alkenes with an iodonium ylide has been developed. The copper source, hypervalent iodine source, solvent, and additives all have a significant effect on the yields and enantioselectivities. High enantioselectivity (up to 99:1 er) and diastereoselectivity (95:5 dr trans/cis) were achieved for a wide range of alkenes. Conditions were developed to convert the trans products to the cis isomers. In addition, 1-nitrocyclopropyl carboxylates were transformed into the corresponding substituted cyclopropane amino acids and aminocyclopropanes. Moreover, a comparative study between Zn- and In-mediated reduction reactions of the nitro group in these compounds with regards to the er erosion in the process is also documented.