1374348-24-9

Basic information

• Product Name: 2-(pyridin-3-yl)-5-(p-tolylethynyl)-1,3,4-oxadiazole
• Synonyms: 2-(pyridin-3-yl)-5-(p-tolylethynyl)-1,3,4-oxadiazole
• CAS NO: 1374348-24-9
• Molecular Weight: 261.283
• Mol File: 1374348-24-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(pyridin-3-yl)-5-(p-tolylethynyl)-1,3,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(pyridin-3-yl)-5-(p-tolylethynyl)-1,3,4-oxadiazole(1374348-24-9)
• EPA Substance Registry System: 2-(pyridin-3-yl)-5-(p-tolylethynyl)-1,3,4-oxadiazole(1374348-24-9)

Safety Data

• Hazardous Substances Data: 1374348-24-9(Hazardous Substances Data)

Upstream product

• 65943-95-5 2-(pyridin-3-yl)-1,3,4-oxadiazole 
• 2227-58-9 3-(4-methylphenyl)prop-2-ynoic acid 
• 104-87-0 4-methyl-benzaldehyde 
• 553-53-7 Nicotinic acid hydrazide 

Relevant articles and documents

Copper-mediated C-H activation of 1,3,4-oxadiazoles with 1,1-dibromo-1-alkenes using PEG-400 as a solvent medium: Distinct approach for the alkynylation of 1,3,4-oxadiazoles

The direct C-H alkynylation of 1,3,4-oxadiazoles with 1,1-dibromo-1-alkenes has been accomplished by using a combination of CuBr/LiOtBu in PEG-400 (a green solvent) at 80 °C. The products were formed in high yields (73-86%) in 2 h. No additional ligand or volatile solvent was required and the conversion was ecofriendly. The direct C-H alkynylation of 1,3,4-oxadiazoles with 1,1-dibromo-1-alkenes has been accomplished by using a combination of CuBr/LiOtBu in PEG-400 (a green solvent) at 80 °C. The products were formed in high yields (73-86%) in 2 h. No additional ligand or volatile solvent was required and the conversion was ecofriendly. Copyright