137435-98-4

Basic information

• Product Name: Toluene-4-sulfonic acid (E)-(3R,6R)-6-((1aR,3aR,3bS,5aR,6R,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-2,3-dimethyl-hept-4-enyl ester
• CAS NO: 137435-98-4
• Molecular Weight: 582.888
• Mol File: 137435-98-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Toluene-4-sulfonic acid (E)-(3R,6R)-6-((1aR,3aR,3bS,5aR,6R,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-2,3-dimethyl-hept-4-enyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Toluene-4-sulfonic acid (E)-(3R,6R)-6-((1aR,3aR,3bS,5aR,6R,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-2,3-dimethyl-hept-4-enyl ester(137435-98-4)
• EPA Substance Registry System: Toluene-4-sulfonic acid (E)-(3R,6R)-6-((1aR,3aR,3bS,5aR,6R,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-2,3-dimethyl-hept-4-enyl ester(137435-98-4)

Safety Data

• Hazardous Substances Data: 137435-98-4(Hazardous Substances Data)

Upstream product

• 81477-26-1 6β-methoxy-3α,5-cyclo-26,27-bisnor-5α-cholest-23(Z)-en-22β-ol 
• 25819-77-6 (20S)-6β-methoxy-3α,5-cyclo-5α-pregnane-20-carbaldehyde 
• 189013-48-7 (22E)-6β-methoxy-3α,5-cyclo-24-α-methyl-5α-cholest-22-en-26-ol 
• 98-59-9 p-toluenesulfonyl chloride 
• 96572-94-0 (E)-(3S,6R)-6-((1aR,3aR,3bS,5aR,6R,8aS,8bS,10R,10aR)-10-Methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-2,3-dimethyl-hept-4-en-1-ol 
• 96615-21-3 (22E)-6β-methoxy-3α,5-cyclo-24-α-methyl-5α-cholest-22-en-26-oic acid ethyl ester 
• 81477-23-8 6β-methoxy-3α,5-cyclo-26,27-bisnor-5α-cholest-23(Z)-en-22α-ol 
• 81477-14-7 6β-methoxy-3α,5-cyclo-26,27-bisnor-5α-cholest-23-yn-22α-ol 
• 81477-15-8 6β-methoxy-3α,5-cyclo-26,27-bisnor-5α-cholest-23-yn-22β-ol 

Downstream Products

• 139403-46-6 6β-methoxy-3α,5-cyclo-24-α-methyl-5α-cholestane 

Relevant articles and documents

[3,3]-Claisen rearrangements in 24α-methyl steroid synthesis: Application to campesterol, crinosterol, and Δ25-crinosterol side chain construction

This paper elaborates an improved synthesis of crinosterol and campesterol starting from stigmasterol. The proposed approach is based on Claisen rearrangement of Δ23-22-allylic alcohols with various configurations of the 22-hydroxy group and ge