1374515-81-7

Basic information

• Product Name: 3-(4-((4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid
• Synonyms: 3-(4-((4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid
• CAS NO: 1374515-81-7
• Molecular Weight: 346.426
• Mol File: 1374515-81-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(4-((4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-((4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid(1374515-81-7)
• EPA Substance Registry System: 3-(4-((4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid(1374515-81-7)

Safety Data

• Hazardous Substances Data: 1374515-81-7(Hazardous Substances Data)

Upstream product

• 61846-68-2 N,N-dimethyl-1-(4'-methyl-[1,1'-biphenyl]-2-yl)methanamine 
• 10175-33-4 1-(2-iodophenyl)-N,N-dimethylmethanamine 
• 103-83-3 N,N'-dimethylbenzylamine 
• 59473-45-9 2-(chloromethyl)iodobenzene 
• 5597-50-2 3-(4-hydroxyphenyl)propionic acid methyl ester 
• 1374516-13-8 methyl 3-(4-((4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoate 
• 1236109-77-5 methyl 3-(4-((2-iodobenzyl)oxy)phenyl)propanoate 

Relevant articles and documents

Making Dimethylamino a Transformable Directing Group by Nickel-Catalyzed C-N Borylation

The dimethylamino (Me2N) group is arguably the most versatile functional group capable of highly efficient and site-selective directed aromatic functionalizations at the ortho-, meta-, and para-positions depending on reaction conditions. While the repertoire of Me2N-directed reactions is growing at a rapid pace, the lack of a general method to transform this group to other functionalities hampers its wider application in organic synthesis. Here we report nickel-catalyzed C-N borylations of aryl- and benzyl-dimethylamines that permit the conversion of a huge library of largely underutilized Me2N-containing organic molecules into various functional molecules by taking advantage of the wealth of existing C-B functionalization methods.