10175-33-4

Basic information

• Product Name: N,N-Dimethyl(2-iodophenyl)methylamine
• Synonyms: N,N-Dimethyl(2-iodophenyl)methylamine;N,N-Dimethyl-2-iodobenzylamine;1-(2-Iodophenyl)-N,N-dimethylmethanamine
• CAS NO: 10175-33-4
• Molecular Formula: C₉H₁₂IN
• Molecular Weight: 261.10275
• Mol File: 10175-33-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N,N-Dimethyl(2-iodophenyl)methylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Dimethyl(2-iodophenyl)methylamine(10175-33-4)
• EPA Substance Registry System: N,N-Dimethyl(2-iodophenyl)methylamine(10175-33-4)

Safety Data

• Hazardous Substances Data: 10175-33-4(Hazardous Substances Data)

Upstream product

• 615-37-2 ortho-methylphenyl iodide 
• 124-40-3 dimethyl amine 
• 54616-46-5 2-Iodo-N,N-dimethylbenzamide 
• 1976-04-1 2-bromo-N,N-dimethylbenzylamine 
• 59473-45-9 2-(chloromethyl)iodobenzene 
• 103-83-3 N,N'-dimethylbenzylamine 

Downstream Products

• 1374516-13-8 methyl 3-(4-((4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoate 
• 1374515-81-7 3-(4-((4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 
• 128638-83-5 (1R,2R,3aS,8aS)-5-(2-t-butyldimethylsilyloxyethyl)-2-t-butyldiphenylsilyloxy-1-methyl-8a-phenylsulfonyl-1,2,3,3a,8,8a-hexahydrocyclopentindene 
• 128666-75-1 (1S,4R)-4-(t-butyldiphenylsilyloxy)-1-(1-chloromethyl-2-phenyl)-2-phenylsulfonylcyclopent-2-ene 
• 128638-84-6 3-(2-chloromethylphenyl)-cyclohexanone 
• 59473-45-9 2-(chloromethyl)iodobenzene 

Relevant articles and documents

Graphene-enhanced platinum-catalysed hydrosilylation of amides and chalcones: A sustainable strategy allocated with in situ heterogenization and multitask application of H2PtCl6

We describe a new sustainable strategy for the comprehensive utilization of a platinum catalyst in different organic transformations, in which an organosilicon/graphene-supported platinum catalyst prepared from a simple hydrosilylation-type reduction could be further used in the 1,4-hydrosilylation of chalcones. The rationally designed and in situ formed Pt@G@Si nanocatalyst is demonstrated to be highly effective in the 1,4-hydrosilylation of α,β-unsaturated enones, allowing for the facile synthesis of a variety of otherwise inaccessible substituted silyl enolates. In addition, with the aid of platinum catalyst residue and TBAF, the one-pot downstream Michael addition of substituted silyl enolates to alkyl acrylates is also reported in this work.

Oxidant-Free Au(I)-Catalyzed Halide Exchange and Csp2-O Bond Forming Reactions

Au has been demonstrated to mediate a number of organic transformations through the utilization of its π Lewis acid character, Au(I)/Au(III) redox properties or a combination of both. As a result of the high oxidation potential of the Au(I)/Au(III) couple, redox catalysis involving Au typically requires the use of a strong external oxidant. This study demonstrates unusual external oxidant-free Au(I)-catalyzed halide exchange (including fluorination) and Csp2-O bond formation reactions utilizing a model aryl halide macrocyclic substrate. Additionally, the halide exchange and Csp2-O coupling reactivity could also be extrapolated to substrates bearing a single chelating group, providing further insight into the reaction mechanism. This work provides the first examples of external oxidant-free Au(I)-catalyzed carbon-heteroatom cross-coupling reactions.

ISOTOPE EXCHANGE OF IODINE IN INACTIVATED IODINE DERIVATIVES OF BENZENE, CATALYZED BY COPPER SALT

The isotope exchange of iodine in some aromatic iodine compounds was investigated in the presence of copper salts in various solvents at 76.5 deg C.It was shown that monovalent copper is responsible for the catalysis during isotope exchange.The isotope exchange is due to intramolecular coordination of the Cu1+ ion with a molecule of the aromatic iodine compounds.A scheme for the isotope exchange of iodine in iodoarenes in the presence of copper salts, using the idea of a one-electron transfer and coordination action between the d10 metals and the ? systems, is proposed and discussed.