1374666-32-6 Usage
Uses
Used in Pharmaceutical Industry:
Mal-PEG2-acid is used as a conjugation agent for the attachment of therapeutic biomolecules to drug carriers. The maleimide group facilitates the covalent linkage with thiol-containing biomolecules, while the terminal carboxylic acid allows for the formation of stable amide bonds with primary amine groups on drug carriers, enhancing the stability and bioavailability of the conjugated therapeutic agents.
Used in Diagnostic Industry:
In the diagnostic field, Mal-PEG2-acid is used as a component in the development of imaging agents. The ability to form covalent bonds with biomolecules and drug carriers enables the creation of targeted imaging agents that can be used for various diagnostic applications, such as detecting specific diseases or monitoring the progress of a treatment.
Used in Research and Development:
Mal-PEG2-acid serves as a valuable tool in research and development for the creation of novel bioconjugates. Its unique properties allow for the design and synthesis of new molecules with specific functions, such as targeted drug delivery systems, biosensors, and other bioanalytical tools.
Used in Drug Delivery Systems:
Mal-PEG2-acid is used as a key component in the development of drug delivery systems, particularly for the attachment of therapeutic agents to nanoparticles or other drug carriers. The formation of stable covalent and amide bonds ensures the efficient delivery of the therapeutic agent to the target site, reducing side effects and improving the overall efficacy of the treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 1374666-32-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,4,6,6 and 6 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1374666-32:
(9*1)+(8*3)+(7*7)+(6*4)+(5*6)+(4*6)+(3*6)+(2*3)+(1*2)=186
186 % 10 = 6
So 1374666-32-6 is a valid CAS Registry Number.
1374666-32-6Relevant academic research and scientific papers
A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS
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, (2021/03/02)
The present invention relates to the conjugation of a tubulysin analog compound to a cell-binding molecule with branched/side-chain linkers for having better delivery of the conjugate compound and targeted treatment of abnormal cells. It also relates to a branched-linkage method of conjugation of a tubulysin analog molecule to a cell-binding ligand, as well as methods of using the conjugate in targeted treatment of cancer, infection and autoimmune disease.
