1374673-07-0

Upstream product

• 1374645-65-4 [4-(4-fluorophenyl)-1-methyl-1H-1,2,3-triazol-5-yl]methanol 
• 1374645-63-2 5-(4-fluoro-phenyl)-3-trimethylsilanylmethyl-3H-[1,2,3]triazole-4-carboxylic acid ethyl ester 
• 1374645-64-3 [5-(4-fluoro-phenyl)-3-trimethylsilanylmethyl-3H-[1,2,3]triazol-4-yl]-methanol 
• 1999-00-4 ethyl 3-(4'-fluorophenyl)-3-oxopropionate 
• 1736-31-8 ethyl 3-(4-fluorophenyl)propiolate 
• 1374672-35-1 6-[5-(4-fluoro-phenyl)-3-methyl-3H-[1,2,3]triazol-4-ylmethoxy]-pyridazine-3-carboxylic acid ethyl ester 
• 1374673-05-8 3-chloro-6-[5-(4-fluoro-phenyl)-3-methyl-3H-[1,2,3]triazol-4-ylmethoxy]-pyridazine 
• 1374672-80-6 (3-methyl-5-phenyl-3H-[1,2,3]triazol-4-yl)-methanol 
• 1374672-79-3 3-methyl-5-phenyl-3H-[1,2,3]triazole-4-carbaldehyde 
• 1352807-56-7 4-phenyl-1-((trimethylsilyl)methyl)-1H-1,2,3-triazole 
• 15965-36-3 1-methyl-4-phenyl-1H-1,2,3-triazole 
• 536-74-3 phenylacetylene 

Downstream Products

• 1374672-36-2 6-[5-(4-Fluoro-phenyl)-3-methyl-3H-[1,2,3]triazol-4-ylmethoxy]-pyridazine-3-carboxylic acid (tetrahydro-pyran-4-yl)-amide 

Relevant academic research and scientific papers

TRIAZOLE DERIVATIVES AND THEIR USE FOR NEUROLOGICAL DISORDERS

The present invention is concerned with novel triazole compounds of formula (I) wherein A, X, Y, Z, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active compounds of present invention have affinity and selectivity for the GABA A α5 receptor. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.

NOVEL TRIAZOLE COMPOUNDS I

The present invention is concerned with novel triazole compounds of formula (I) wherein A, X, Y, Z, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active compounds of present invention have affinity and selectivity for the GABA A α5 receptor. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.