1374694-30-0

Basic information

• Product Name: C₅₉H₆₀N₂O₂₈
• Synonyms: C₅₉H₆₀N₂O₂₈
• CAS NO: 1374694-30-0
• Molecular Weight: 1245.12
• Mol File: 1374694-30-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₅₉H₆₀N₂O₂₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₉H₆₀N₂O₂₈(1374694-30-0)
• EPA Substance Registry System: C₅₉H₆₀N₂O₂₈(1374694-30-0)

Safety Data

• Hazardous Substances Data: 1374694-30-0(Hazardous Substances Data)

Upstream product

• 1352435-33-6 C₂₉H₃₉NO₁₃Si 
• 1352435-32-5 C₂₃H₂₅NO₁₃ 
• 1352435-38-1 C₃₈H₃₆N₂O₂₀ 
• 25316-40-9 doxorubicin hydrochloride 
• 1313026-26-4 rac-4-(1-hydroxybut-3-yn-1-yl)-2-nitrophenol 

Downstream Products

• 1374694-31-1 C₈₁H₁₀₆N₆O₃₈ 

Relevant articles and documents

Synthesis and antitumor efficacy of a β-glucuronidase-responsive albumin-binding prodrug of doxorubicin

In this paper we describe the synthesis and biological evaluation of the first β-glucuronidase-responsive albumin-binding prodrug designed for the selective delivery of doxorubicin at the tumor site. This prodrug leads to superior antitumor efficacy in mice compared to HMR 1826, a well-known glucuronide prodrug of doxorubicin that cannot bind covalently to circulating albumin. Furthermore, this compound inhibits tumor growth in a manner similar to that of doxorubicin while avoiding side effects induced by the free drug.