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Product FOB Price Min.Order Supply Ability Supplier
Doxorubicin hydrochloride
Cas No: 25316-40-9
No Data 1 Gram 10 Kilogram/Week Hangzhou J&H Chemical Co., Ltd. Contact Supplier
Doxorubicin hydrochloride CAS NO.25316-40-9
Cas No: 25316-40-9
No Data 1 Kilogram 500~1000 Kilogram/Month Hubei Jusheng Technology Co., Ltd., Contact Supplier
doxorubicin hydrochloride
Cas No: 25316-40-9
No Data No Data 5 Kilogram/Month ningbo easun bio-tech co., ltd Contact Supplier
DOX 25316-40-9 supplier
Cas No: 25316-40-9
No Data 1 Milligram 100 Metric Ton/Year Nanjing Sunsure Chemical Technology Co., Ltd Contact Supplier
High quality Doxorubicin hydrochloride99%
Cas No: 25316-40-9
USD $ 10.0-10.0 / Gram 10 Gram 10000 Gram/Month Shanghai Upbio Tech Co.,Ltd Contact Supplier
Doxorubicin hydrochloride 25316-40-9
Cas No: 25316-40-9
No Data 1 Kilogram 1000 Kilogram/Month Shaanxi WuZhiYuan Biological Technology Co.,Ltd Contact Supplier
High Purity Powder Doxorubicin hcl / Hydrochloride
Cas No: 25316-40-9
USD $ 10.0-20.0 / Gram 1 Gram 5 Kilogram/Month Beijing Yibai Biotechnology Co., Ltd Contact Supplier
Doxorubicin hydrochloride competitive price and good quality
Cas No: 25316-40-9
USD $ 200.0-200.0 / Gram 1 Gram 1 Kilogram/Month Beijing Mesochem Technology Co.,LTD Contact Supplier
Doxorubicin hydrochloride
Cas No: 25316-40-9
No Data No Data Metric Ton/Day TAIZHOU SHASIN PHARMACHEM CO.,LTD Contact Supplier
Doxorubicin hydrochloride CAS NO.25316-40-9
Cas No: 25316-40-9
USD $ 1.0-3.0 / Metric Ton 1 Metric Ton 10 Metric Ton/Day Hebei yanxi chemical co.,LTD. Contact Supplier

25316-40-9 Usage

Uses

Doxorubicin is an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. By intercalating within DNA, doxorubicin inhibits nucleic acid synthesis and induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein.[Cayman Chemical]

Biological Activity

Antitumor antibiotic agent that inhibits DNA topoisomerase II. DNA intercalator that inhibits nucleic acid synthesis and induces apoptosis.

Air & Water Reactions

Water soluble.

General Description

Orange-red thin needles. Aqueous solutions yellow-orange at acid pHs, orange-red at neutral pHs, and violet blue over pH 9.

Uses

Antibacterial;DNA intercalant

Uses

Doxorubicin hydrochloride (adriamycin hydrochloride) is an antitumor agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently.

Chemical Properties

Orange-Red Crystalline Solid

Fire Hazard

Doxorubicin hydrochloride is probably combustible.

Uses

Doxorubicin hydrochloride (adriamycin hydrochloride) is an antitumour agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently.

Uses

Used as an antineoplastic

Uses

Strong fluorescent dye intercalating into DNA. Antitumour antibiotic. Effect of adriamycin on heart mitochondrial DNA. Inhibitor of reverse transcriptase and RNA polymerase; immunosuppressive agent.

Reactivity Profile

Amines, like Doxorubicin hydrochloride, are weak chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Brand name

Adriamycin (Pharmacia & Upjohn); Doxil (ALZA); Rubex (Bristol-Myers Squibb).
InChI:InChI=1/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1

25316-40-9 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
TCI America (D4193)  Doxorubicin Hydrochloride  >95.0%(HPLC) 25316-40-9 100mg 4,480.00CNY Detail
TCI America (D4193)  Doxorubicin Hydrochloride  >95.0%(HPLC) 25316-40-9 25mg 1,490.00CNY Detail

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