137487-81-1

Upstream product

• 67-56-1 methanol 
• 117554-03-7 (4R,5R)-5-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-4-((S)-1-phenyl-ethylamino)-dihydro-furan-2-one 
• 2627-86-3 (S)-1-phenyl-ethylamine 

Downstream Products

• 137487-82-2 (R)-4,4-Dimethoxy-3-((S)-1-phenyl-ethylamino)-butyric acid 
• 137487-84-4 (R)-4-Dimethoxymethyl-1-((S)-1-phenyl-ethyl)-azetidin-2-one 

Relevant academic research and scientific papers

Asymmetric synthesis of β-lactams via amine additions to 5(R)-menthyloxy-2[5H]-furanone

The enantioselective synthesis of a N-benzyl substituted β-lactam 5a, a precursor for carbapenem antibiotics, starting from the chiral synthon 5(R)-menthyloxy-2[5H]-furanone 1, is described.