1374968-23-6

Basic information

• Product Name: 1'-(4-benzoylphenyl)-3'-O-(2-cyanoethoxy(diisopropylamino)phosphanyl)-5'-O-(dimethoxytrityl)-1',2'-dideoxyribofuranose
• Synonyms: 1'-(4-benzoylphenyl)-3'-O-(2-cyanoethoxy(diisopropylamino)phosphanyl)-5'-O-(dimethoxytrityl)-1',2'-dideoxyribofuranose
• CAS NO: 1374968-23-6
• Molecular Weight: 800.932
• Mol File: 1374968-23-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1'-(4-benzoylphenyl)-3'-O-(2-cyanoethoxy(diisopropylamino)phosphanyl)-5'-O-(dimethoxytrityl)-1',2'-dideoxyribofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1'-(4-benzoylphenyl)-3'-O-(2-cyanoethoxy(diisopropylamino)phosphanyl)-5'-O-(dimethoxytrityl)-1',2'-dideoxyribofuranose(1374968-23-6)
• EPA Substance Registry System: 1'-(4-benzoylphenyl)-3'-O-(2-cyanoethoxy(diisopropylamino)phosphanyl)-5'-O-(dimethoxytrityl)-1',2'-dideoxyribofuranose(1374968-23-6)

Safety Data

• Hazardous Substances Data: 1374968-23-6(Hazardous Substances Data)

Upstream product

• 59793-76-9 2-(4-bromophenyl)-2-phenyl-1,3-dioxolane 
• 90-90-4 (4-bromophenyl)(phenyl)methanone 
• 1374968-22-5 1'-(4-benzoylphenyl)-5'-O-(dimethoxytrityl)-1',2'-dideoxyribofuranose 
• 124482-92-4 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine 
• 1374968-21-4 1'-(4-benzoylphenyl)-1',2'-dideoxyribofuranose 

Relevant articles and documents

Synthesis of a benzophenone C-nucleoside as potential triplet energy and charge donor in nucleic acids

A synthetic route to the C-nucleoside that bears benzophenone as a DNA base substitution directly at the anomeric center of the 2′- deoxyribofuranoside was worked out. Furthermore, the -anomer of this artificial nucleoside was converted synthetically into the corresponding DNA building block and incorporated into two representative oligonucleotides by automated phosphoramidite chemistry. The chromophore-modified DNA was characterized by methods of optical spectroscopy. The absorption band at ～350 nm can be used for selective excitation of the benzophenone chromophore outside the nucleic acid absorption range, which makes the benzophenone nucleoside potentially useful for photochemical and photobiological applications. Georg Thieme Verlag Stuttgart · New York.