137530-19-9

Upstream product

• 54848-33-8 (S)-tetrahydro-5-oxo-2-furancarbonyl chloride 
• 21461-84-7 (2S)-tetrahydro-5-oxofuran-2-carboxylic acid 
• 137530-18-8 (S)-5-(2'-cyclohexyl-1'-oxoethyl)dihydrofuran-2(3H)-one 

Downstream Products

• 137530-20-2 (5S,1'S)-5-(2'-cyclohexyl-1'-methanesulfonyloxyethyl)dihydrofuran-2(3H)-one 
• 132094-22-5 (3R,5S,1'S)-5-(1'-tert-butoxycarbonylamino-2'-cyclohexylethyl)-3-methyldihydrofuran-2(3H)-one 
• 137530-21-3 (5S,1'R)-5-(1'-bromo-2'-cyclohexylethyl)dihydrofuran-2(3H)-one 
• 125218-53-3 (5S,1'S)-5-(1'-azido-2'-cyclohexylethyl)dihydrofuran-2(3H)-one 

Relevant academic research and scientific papers

Studies of HIV-1 protease inhibitors. II. Incorporation of four types of hydroxyethylene dipeptide isosteres at the scissile site of substrate sequences

Human immunodeficiency virus type 1 (HIV-1) protease inhibitors containing four types of hydroxyethylene dipeptide isosteres were designed and synthesized. These inhibitors consist of eight stereoisomers of phenylalanylproline (Phe-Ψ[H.E.]-Pro), four ster