1375479-05-2

Basic information

• Product Name: 1-benzyloxy-3-bromo-2-iodobenzene
• Synonyms: 1-benzyloxy-3-bromo-2-iodobenzene
• CAS NO: 1375479-05-2
• Molecular Weight: 389.03
• Mol File: 1375479-05-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-benzyloxy-3-bromo-2-iodobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyloxy-3-bromo-2-iodobenzene(1375479-05-2)
• EPA Substance Registry System: 1-benzyloxy-3-bromo-2-iodobenzene(1375479-05-2)

Safety Data

• Hazardous Substances Data: 1375479-05-2(Hazardous Substances Data)

Upstream product

• 855836-52-1 3-bromo-2-iodophenol 
• 100-39-0 benzyl bromide 
• 54655-07-1 lithium trimethylsilylacetylenide 
• 138720-02-2 3-benzyloxy-2-iodophenol trifluoromethanesulfonate 

Relevant articles and documents

INDOLE DERIVATIVES AS ALPHA-1 -ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1 -ANTITRYPSIN DEFICIENCY (AATD)

Indole derivatives as alpha-l-antitrypsin modulators for treating alpha-l-antitrypsin deficiency (AATD).

Catalytic generation of arynes and trapping by nucleophilic addition and iodination

A fair exchange: In the title reaction, alkynyllithium serves as an initiator for benzyne generation through an iodine-lithium exchange (see scheme; Tf=trifluoromethanesulfonyl). When performed in the presence of stoichiometric amounts of a nucleophile, the generated benzyne undergoes attack by lithio nucleophiles to generate aryllithium, which is then iodinated by iodoalkyne to give the iodoarenes 1. Copyright