855836-52-1

Basic information

• Product Name: 3-BROMO-2-IODOPHENOL
• Synonyms: 3-BROMO-2-IODOPHENOL
• CAS NO: 855836-52-1
• Molecular Formula: C₆H₄BrIO
• Molecular Weight: 298.9
• Product Categories: pharmacetical
• Mol File: 855836-52-1.mol
• Article Data: 7

Chemical Properties

• Melting Point: 85℃
• Boiling Point: 243.9°C at 760 mmHg
• Flash Point: 101.3°C
• Appearance: /
• Density: 2.369g/cm³
• Vapor Pressure: 0.0201mmHg at 25°C
• Refractive Index: 1.699
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 7.55±0.10(Predicted)
• CAS DataBase Reference: 3-BROMO-2-IODOPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-2-IODOPHENOL(855836-52-1)
• EPA Substance Registry System: 3-BROMO-2-IODOPHENOL(855836-52-1)

Safety Data

• Hazardous Substances Data: 855836-52-1(Hazardous Substances Data)

Usage

General Description

3-Bromo-2-iodophenol is a chemical compound with the molecular formula C6H4BrIO. It is a halogenated phenol derivative, containing both bromine and iodine atoms attached to a benzene ring. 3-BROMO-2-IODOPHENOL is commonly used as a reagent in organic synthesis, specifically in the preparation of various pharmaceuticals, agrochemicals, and fine chemicals. 3-Bromo-2-iodophenol is also known for its potential application as a substrate for various catalytic reactions in organic chemistry. Additionally, it has been investigated for its potential biological activities and has shown promise as a building block for the synthesis of novel biologically active compounds. Due to its unique structure and reactivity, 3-Bromo-2-iodophenol is an important intermediate in the production of various organic compounds used in a wide range of industries.

InChI:InChI=1/C6H4BrIO/c7-4-2-1-3-5(9)6(4)8/h1-3,9H

Upstream product

• 591-20-8 3-Bromophenol 
• 450412-22-3 1-bromo-2-iodo-3-methoxybenzene 
• 1369625-51-3 2-(diisopropyl(phenyl)silyl)pyrimidine 
• 591-50-4 iodobenzene 
• 75-25-2 Bromoform 
• 33948-35-5 2-iodo-cyclopent-2-enone 
• 1369625-72-8 2-[(2-bromophenyl)(diisopropyl)silyl]pyrimidine 
• 2398-37-0 3-methoxyphenyl bromide 
• 863870-72-8 O-3-bromophenyl N,N-diethylcarbamate 
• 863870-79-5 O-3-bromo-2-iodophenyl N,N-diethylcarbamate 
• 116435-77-9 2-amino-3-bromophenol 

Downstream Products

• 14400-94-3 2,3,4,6-tetrabromophenol 
• 1287791-68-7 2-(3-bromo-2-iodophenoxy)-2-methylpropanamide 
• 52488-36-5 4-bromo-1H-indole 
• 1244651-60-2 N-[3-bromo-2-(hex-1-yn-1-yl)phenyl]-2-hydroxy-2-methylpropanamide 
• 1244651-64-6 N-(3-bromo-2-(hept-1-ynyl)phenyl)-2-hydroxy-2-methylpropanamide 
• 1244651-69-1 N-(3-bromo-2-(2-(trimethylsilyl)ethynyl)phenyl)-2-hydroxy-2-methylpropanamide 
• 1244651-72-6 N-(3-bromo-2-(2-(thiophen-3-yl)ethynyl)phenyl)-2-hydroxy-2-methylpropanamide 
• 1244652-11-6 4-bromo-2-(3-chlorophenyl)-1H-indole 
• 1244651-37-3 N-(3-bromo-2-iodophenyl)-2-hydroxy-2-methylpropanamide 
• 1287792-00-0 2-phenyl-4-(2-phenylethynyl)-1H-indole 
• 1287792-08-8 4-bromo-2-butyl-3-(phenylthio)-1H-indole 
• 1287792-10-2 2-butyl-4-phenyl-1H-indole 
• 1006715-24-7 3-bromo-2-iodophenol methoxymethyl ether 
• 1375479-05-2 1-benzyloxy-3-bromo-2-iodobenzene 

Relevant articles and documents

An Efficient and Modular Route to C 3?-TunePhos-Type Ligands

An efficient and modular synthetic route to the bidentate C 3?-TunePhos was developed, which allowed tunable steric and electronic effects of the ligands. This novel chemical technology highlights a versatile C 3?-dibromodiphenyl int

Twofold unsymmetrical C-H functionalization of PyrDipSi-substituted arenes: A general method for the synthesis of substituted meta-halophenols

And the world is your oyster Sequential halogenation/oxygenation reactions of 2-diisopropylsilylpyrimidine-substituted arenes provide a general and efficient synthesis of substituted meta-halophenols from simple aryl iodides (see scheme; Piv=pivaloyl). The products are poised to undergo diverse C-C, C-N, and C-O bond-forming reactions that enable the transformation of their framework and the introduction of valuable functionalities. Copyright

Synthesis of 4-functionalized-1H-indoles from 2,3-dihalophenols

A new synthesis of 4-halo-1H-indoles has been developed from easily available 2,3-dihalophenol derivatives. The key steps are Smiles rearrangement and a one-pot or stepwise Sonogashira coupling/NaOH-mediated cyclization. Subsequent functionalization allows access to a wide variety of 2,4- or 2,3,4-regioselectively functionalized indoles.