137583-05-2

Basic information

• Product Name: 2-Ethanediamine,N-2-pyrimidinyl-
• Synonyms: 2-Ethanediamine,N-2-pyrimidinyl-;1,2-Ethanediamine, N-2-pyrimidinyl- (9CI);N-(2-aminoethyl)-N-pyrimidin-2-ylamine;N1-(PyriMidin-2-yl)ethane-1,2-diaMine;N1-2-pyrimidinyl-1,2-Ethanediamine;N1-(Pyrimidin-2-yl)
• CAS NO: 137583-05-2
• Molecular Formula: C₆H₁₀N₄
• Molecular Weight: 138.1704
• Product Categories: PYRIMIDINE;AMINESECONDARY
• Mol File: 137583-05-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 294.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.196±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 9.23±0.10(Predicted)
• CAS DataBase Reference: 2-Ethanediamine,N-2-pyrimidinyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Ethanediamine,N-2-pyrimidinyl-(137583-05-2)
• EPA Substance Registry System: 2-Ethanediamine,N-2-pyrimidinyl-(137583-05-2)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 137583-05-2(Hazardous Substances Data)

Usage

General Description

2-Ethanediamine,N-2-pyrimidinyl- is a chemical compound with the molecular formula C6H12N4. It is also known as ethephon, and is commonly used as a plant growth regulator. When applied to plants, it is converted into ethylene, which stimulates the ripening of fruits and the shedding of leaves. Additionally, it can also be used to promote flowering, improve fruit set, and enhance the color development in fruits. 2-Ethanediamine,N-2-pyrimidinyl- is considered to be a safe and effective way to control the growth and development of various plants, and is widely used in commercial agriculture and horticulture. However, it is important to follow proper application and safety guidelines when using this chemical to avoid any potential negative effects on human health or the environment.

Upstream product

• 1722-12-9 2-chloropyrimidine 
• 57260-73-8 N-BOC-1,2-diaminoethane 
• 584-08-7 potassium carbonate 
• 107-15-3 ethylenediamine 

Downstream Products

• 138490-79-6 4-[(methylsulfonyl)amino]-N-[2-(2-pyrimidinylamino)ethyl]benzenesulfonamide 

Relevant articles and documents

From Experiments to a Fast Easy-to-Use Computational Methodology to Predict Human Aldehyde Oxidase Selectivity and Metabolic Reactions

Aldehyde oxidase (AOX) is a molibdo-flavoenzyme that has raised great interest in recent years, since its contribution in xenobiotic metabolism has not always been identified before clinical trials, with consequent negative effects on the fate of new potential drugs. The fundamental role of AOX in metabolizing xenobiotics is also due to the attempt of medicinal chemists to stabilize candidates toward cytochrome P450 activity, which increases the risk for new compounds to be susceptible to AOX nucleophile attack. Therefore, novel strategies to predict the potential liability of new entities toward the AOX enzyme are urgently needed to increase effectiveness, reduce costs, and prioritize experimental studies. In the present work, we present the most up-to-date computational method to predict liability toward human AOX (hAOX), for applications in drug design and pharmacokinetic optimization. The method was developed using a large data set of homogeneous experimental data, which is also disclosed as Supporting Information.

SUBSTITUTED 2H-[1,2,4]TRIAZOLO[4,3-A]PYRAZINES AS GSK-3 INHIBITORS

The invention relates to compounds of formula (I) prodrugs thereof, and the pahrmaceutically acceptabel salts of the compounds and prodrugs, wherein Ra, Rb, R1 and R2 are as defined herein; pharmaceutical compositions thereof; and uses thereof.

Substituted 4-amino[1,2,4]triazolo[4,3-a] quinoxalines

The present invention provides compounds of formula (I) the prodrugs thereof, and the pharmaceutically acceptable salts of the compounds and prodrugs, wherein Ra, Rb, R1, and R2 are as defined herein; pharmaceutical compositions thereof; and uses thereof.