137587-06-5

Basic information

• Product Name: 2-Cyclopropyl-3-ethynyl-4-(4-fluoro-phenyl)-5-methyl-6-phenyl-pyridine
• Synonyms: 2-Cyclopropyl-3-ethynyl-4-(4-fluoro-phenyl)-5-methyl-6-phenyl-pyridine
• CAS NO: 137587-06-5
• Molecular Weight: 327.401
• Mol File: 137587-06-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Cyclopropyl-3-ethynyl-4-(4-fluoro-phenyl)-5-methyl-6-phenyl-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopropyl-3-ethynyl-4-(4-fluoro-phenyl)-5-methyl-6-phenyl-pyridine(137587-06-5)
• EPA Substance Registry System: 2-Cyclopropyl-3-ethynyl-4-(4-fluoro-phenyl)-5-methyl-6-phenyl-pyridine(137587-06-5)

Safety Data

• Hazardous Substances Data: 137587-06-5(Hazardous Substances Data)

Upstream product

• 24922-02-9 Ethyl 3-cyclopropyl-3-oxopropionate 
• 137586-95-9 α-(1-Cyclopropyl-1-oxomethyl)-β-(4-fluorophenyl)-γ-methyl-Δ-oxophenylpentanoic acid, ethyl ester 
• 137586-96-0 2-Cyclopropyl-4-(4-fluorophenyl)-5-methyl-6-phenyl-3-pyridinecarboxylic acid, ethyl ester 
• 135426-30-1 2-Cyclopropyl-4-(4-fluorophenyl)-5-methyl-6-phenyl-3-pyridinemethanol 
• 137586-97-1 2-Cyclopropyl-4-(4-fluorophenyl)-5-methyl-6-phenyl-3-pyridinecarboxaldehyde 
• 137586-94-8 (Z)-2-Cyclopropanecarbonyl-3-(4-fluoro-phenyl)-acrylic acid ethyl ester 
• 459-57-4 4-fluorobenzaldehyde 
• 135454-81-8 2-cyclopropyl-3-(2,2-dibromoethenyl)-4-(4-fluorophenyl)-5-methyl-6-phenylpyridine 

Downstream Products

• 135426-93-6 (S,E)-4-[[2-[2-Cyclopropyl-4-(4-fluorophenyl)-5-methyl-6-phenyl-3-pyridinyl]ethenyl]hydroxyphosphinyl]-3-hydroxybutanoic acid, disodium salt 
• 135426-94-7 (S)-4-[[[2-Cyclopropyl-4-(4-fluorophenyl)-5-methyl-6-phenyl-3-pyridinyl]ethyl]hydroxyphosphinyl]-3-hydroxybutanoic acid, disodium salt 
• 137604-58-1 (S)-3-(tert-Butyl-diphenyl-silanyloxy)-4-({(E)-2-[2-cyclopropyl-4-(4-fluoro-phenyl)-5-methyl-6-phenyl-pyridin-3-yl]-vinyl}-methoxy-phosphinoyl)-butyric acid methyl ester 
• 137604-59-2 (S)-4-({(E)-2-[2-Cyclopropyl-4-(4-fluoro-phenyl)-5-methyl-6-phenyl-pyridin-3-yl]-vinyl}-methoxy-phosphinoyl)-3-hydroxy-butyric acid methyl ester 
• 137587-07-6 2-Cyclopropyl-3-(2-iodoethenyl)-4-(4-fluorophenyl)-5-methyl-6-phenylpyridine 

Relevant articles and documents

Phosphorus-Containing Inhibitors of HMG-CoA Reductase. 2. Synthesis and Biological Activites of a Series of Substituted Pyrydynes Containing a Hydroxyphosphinyl Moiety

A series of 2,3,4,(5),6-substituted pyridines containing a hydroxyphosphinyl functionality have been prepared and were evaluated for their ability to inhibit the enzyme HMG-CoA reductase.Systematic substitution of both R1-R4 and X-Y