24922-02-9

Basic information

• Product Name: 3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER
• Synonyms: 3-Cyclopropyl-3-oxo-propionicethyl ester;Cyclopropanepropanoic acid, β-oxo-, ethyl ester;β-Oxocyclopropanepropanoic acid ethyl ester;Carbethoxymethyl cyclopropyl ketone;ETHYL 3-CYCLOPROPYL-3-OXO-PROPANOATE;3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER;Ethyl beta-oxo-Cyclopropane Propionate;Ethyl β-oxo-cyclopropanepropionate
• CAS NO: 24922-02-9
• Molecular Formula: C₈H₁₂O₃
• Molecular Weight: 156.18
• Product Categories: NULL;Pitavastatin Calcium Intermediates
• Mol File: 24922-02-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 73℃/1mm
• Flash Point: >96℃
• Appearance: /
• Density: 1.058 g/mL at 25 °C
• Vapor Pressure: 0.169mmHg at 25°C
• Refractive Index: n20/D1.449
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 10.61±0.20(Predicted)
• CAS DataBase Reference: 3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER(24922-02-9)
• EPA Substance Registry System: 3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER(24922-02-9)

Safety Data

• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 24922-02-9(Hazardous Substances Data)

Usage

Uses

Ethyl 3-cyclopropyl-3-oxopropanoate

InChI:InChI=1/C8H12O3/c1-2-11-8(10)5-7(9)6-3-4-6/h6H,2-5H2,1H3

Upstream product

• 765-43-5 Cyclopropyl methyl ketone 
• 105-36-2 ethyl bromoacetate 
• 5500-21-0 cyclopropropanecarbonitrile 

Downstream Products

• 7038-74-6 6-cyclopropyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 859296-67-6 1-phenyl-3-cyclopropyl-5-pyrazolone 
• 137586-94-8 (Z)-2-Cyclopropanecarbonyl-3-(4-fluoro-phenyl)-acrylic acid ethyl ester 
• 87141-66-0 1-Cyclopropyl-3-(4-methoxy-phenyl)-propan-1-one 
• 87141-68-2 ethyl 3-cyclopropyl-2-(3-methoxybenzyl)-3-oxopropanoate 
• 148516-11-4 2-cyclopropyl-4-(4-fluoro-phenyl)-3-quinoline carboxylic acid ethyl ester 
• 148475-68-7 2-(2'-Cyano-biphenyl-4-ylmethyl)-3-cyclopropyl-3-oxo-propionic acid ethyl ester 
• 187827-14-1 3-Amino-3-cyclopropyl-acrylic acid ethyl ester 
• 947271-63-8 5-cyclopropyl-1-phenyl-1H-1,2,3-triazole-4-carboxylic acid 
• 1073483-80-3 ethyl 2-cyclopropyl-5-phenyl-1H-pyrrole-3-carboxylate 
• 954232-87-2 2-Methyl-4-cyclopropylpyrimidine-5-carboxylic acid 
• 857986-63-1 5-cyclopropyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one 

Relevant articles and documents

Phenyl derivatives, their manufacture and use as pharmaceutical agents

This invention relates to compounds of the formula wherein one of R5, R6 and R7 is and X1, X2, Y1 to Y4, R1 to R13 and m and n are defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.