1376189-45-5

Basic information

• Product Name: (R,R)-1-benzyl-2,3-diphenylpiperazine
• Synonyms: (R,R)-1-benzyl-2,3-diphenylpiperazine
• CAS NO: 1376189-45-5
• Molecular Weight: 328.457
• Mol File: 1376189-45-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R,R)-1-benzyl-2,3-diphenylpiperazine(CAS DataBase Reference)
• NIST Chemistry Reference: (R,R)-1-benzyl-2,3-diphenylpiperazine(1376189-45-5)
• EPA Substance Registry System: (R,R)-1-benzyl-2,3-diphenylpiperazine(1376189-45-5)

Safety Data

• Hazardous Substances Data: 1376189-45-5(Hazardous Substances Data)

Upstream product

• 70708-34-8 2,3-diphenylpiperazine 
• 100-39-0 benzyl bromide 
• 104-71-2 N,N'-bis(benzyliden)ethylendiamine 
• 1241681-30-0 (R,R)-tert-butyl-2,3-diphenyl-1-piperazinecarboxylate 
• 1376191-63-7 (R,R)-tert-butyl-4-benzyl-2,3-diphenyl-1-piperazinecarboxylate 

Downstream Products

• 27694-89-9 (R)-1-phenylundeca-1,2-diene 
• 1376191-82-0 C₃₈H₃₄N₂ 

Relevant articles and documents

Highly enantioselective synthesis of chiral allenes by sequential creation of stereogenic center and chirality transfer in a single pot operation

Chiral allenes are readily accessed in a single pot operation in the reaction of terminal alkynes, aldehydes, chiral secondary amines, and zinc halides in good yields (up to 77% yield) and excellent enantioselectivities (up to 99% ee) in toluene at 120 °C. The reaction proceeds through initial formation of chiral propargylamine intermediates with creation of a new stereogenic center and subsequent chirality transfer via an intramolecular hydride shift to produce chiral allenes with high enantiomeric purities.