1376334-38-1

Basic information

• Product Name: 3-(cyclopropylmethyl)-7-[4-(3,6-difluoro-2-methoxyphenyl)-1-piperidinyl]-8-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyridine
• Synonyms: 3-(cyclopropylmethyl)-7-[4-(3,6-difluoro-2-methoxyphenyl)-1-piperidinyl]-8-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyridine
• CAS NO: 1376334-38-1
• Molecular Weight: 466.454
• Mol File: 1376334-38-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(cyclopropylmethyl)-7-[4-(3,6-difluoro-2-methoxyphenyl)-1-piperidinyl]-8-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(cyclopropylmethyl)-7-[4-(3,6-difluoro-2-methoxyphenyl)-1-piperidinyl]-8-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyridine(1376334-38-1)
• EPA Substance Registry System: 3-(cyclopropylmethyl)-7-[4-(3,6-difluoro-2-methoxyphenyl)-1-piperidinyl]-8-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyridine(1376334-38-1)

Safety Data

• Hazardous Substances Data: 1376334-38-1(Hazardous Substances Data)

Upstream product

• 2713-31-7 2,5-difluorophenol 
• 26452-80-2 2,4-dichloropyridine 
• 343781-36-2 2,4-dichloro-3-iodo-pyridine 
• 1186194-98-8 2,4-dichloro-3-(trifluoromethyl)pyridine 
• 1254981-27-5 4-(benzyloxy)-2-chloro-3-(trifluoromethyl)pyridine 
• 1254981-28-6 4-(benzyloxy)-2-hydrazineyl-3-(trifluoromethyl)pyridine 
• 1254981-29-7 N'-[4-(benzyloxy)-3-(trifluoromethyl)pyridin-2-yl]-2-cyclopropylacetohydrazide 
• 1254981-30-0 7-chloro-3-(cyclopropylmethyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine 
• 1254981-53-7 4-(3,6-difluoro-2-methoxy-phenyl)-piperidine 
• 1208076-11-2 2-bromo-1,4-difluoro-3-methoxy-benzene 
• 1254981-51-5 4-(3,6-difluoro-2-methoxy-phenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 1254981-52-6 4-(3,6-difluoro-2-methoxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 375853-82-0 tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate 

Downstream Products

• 1376335-37-3 2-[1-[3-(cyclopropylmethyl)-8-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyridin-7-yl]-4-piperidinyl]-3,6-difluoro-phenol 

Relevant articles and documents

RADIOLABELLED mGluR2 PET LIGANDS

The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo and to precursors of said compounds.

RADIOLABELLED mGLuR2 PET LIGANDS

The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo and to precursors of said compounds.