1376346-52-9Relevant academic research and scientific papers
Enantioselective cyclopropanation of enals by oxidative N-heterocyclic carbene catalysis
Biswas, Anup,De Sarkar, Suman,Tebben, Ludger,Studer, Armido
supporting information; experimental part, p. 5190 - 5192 (2012/06/01)
Carbene catalysed redox activation of α,β-unsaturated aldehydes is applied for generation of α,β-unsaturated acyl azoliums which undergo cyclopropanation upon reaction with a sulfur ylide and an alcohol to give the corresponding cyclopropanecarboxylic acid esters. With chiral carbenes good to excellent diastereo and enantioselectivities are obtained.
