137761-03-6

Basic information

• Product Name: (1R,2S,5R)-8-phenylmenthyl (S)-4-chlorophenylsulfinylacetate
• Synonyms: (1R,2S,5R)-8-phenylmenthyl (S)-4-chlorophenylsulfinylacetate
• CAS NO: 137761-03-6
• Molecular Weight: 433.011
• Mol File: 137761-03-6.mol

Chemical Properties

• CAS DataBase Reference: (1R,2S,5R)-8-phenylmenthyl (S)-4-chlorophenylsulfinylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,5R)-8-phenylmenthyl (S)-4-chlorophenylsulfinylacetate(137761-03-6)
• EPA Substance Registry System: (1R,2S,5R)-8-phenylmenthyl (S)-4-chlorophenylsulfinylacetate(137761-03-6)

Safety Data

• Hazardous Substances Data: 137761-03-6(Hazardous Substances Data)

Upstream product

• 65253-04-5 (-)-8-phenylmenthol 
• 125706-42-5 (S)-(-)-<(4-Chlorophenyl)sulfinyl>acetic acid 

Downstream Products

• 137761-08-1 E-(1R,2S,5R)-8-phenylmenthyl 4-hydroxyhept-2-enoate 

Relevant articles and documents

Stereochemically matched sulfinylacetates for double diastereoselection in the spac reaction

4-Chlorophenylsulfinylacetates of defined stereochemistry at sulfur were prepared from monochiral alcohols: compound 2 from (+)-menthol; 3 and 4 from (-)-8-phenylmenthol; 5 and 6 from (+)-trans-2-phenylcyclohexanol; and, 7 and 9 from (-)-10-dicyclohexylsulfamoyl-D-isoborneol. Reagents for which the sulfoxide asymmetry is matched with the inducing effect of the auxiliary give good diastereoselection in SPAC reactions affording γ-hydroxy-α,β-unsaturatod alcohols of high optical purity. Asymmetry at the sulfoxide has a greater effect than the auxiliaries on the stereochemical outcome of these reactions.