137809-75-7

Upstream product

• 98-88-4 benzoyl chloride 
• 137809-74-6 (S)-2-Hydroxymethyl-2-methyl-4-trimethylsilanyl-cyclopentanone 
• 137893-84-6 (+)-(5S)-3-methyl-5-trimethylsilyl-2-cyclohexenone 
• 145948-60-3 (S)-1-Methyl-2-oxo-4-trimethylsilanyl-cyclopentanecarbaldehyde 
• 137893-79-9 (-)-(2S,3S,5S)-2,3-epoxy-3-methyl-5-(trimethylsilyl)cyclohexanone 

Downstream Products

• 137809-77-9 (-)-(5S)-6-benzoyloxy-5-methyl-5-hexanolide 
• 137809-76-8 (-)-(2S)-benzoyloxymethyl-2-methylcyclopentanone 

Relevant academic research and scientific papers

New route to (-)-frontalin and (-)-malyngolide via epoxyketone rearrangement

Synthesis of the title compounds by utilizing BF3·Et2O catalyzed ring contraction of 2,3-epoxycyclohexanones leading to 2-alkyl-2-formylcyclopentanones is described.