137858-31-2

Upstream product

• 6674-22-2 1,8-diazabicyclo[5.4.0]undec-7-ene 
• 137858-30-1 tert-butyl 4-<2-<<(benzyloxycarbonyl)carbamoyl>methyl>-1-cyclopropyl-5-fluoro-6-benzimidazolyl>-1-piperazinecarboxylate 
• 137858-26-5 ethyl 6-<4-(tert-butoxycarbonyl)-1-piperazinyl>-1-cyclopropyl-5-fluoro-2-benzimidazoleacetate 
• 137858-25-4 tert-butyl 4-<5-cyclopropylamino)-2-fluoro-4-nitrophenyl>-1-piperazinecarboxylate 
• 137858-24-3 1-acetyl-4-<5-(cyclopropylamino)-2-fluoro-4-nitrophenyl>piperazine 
• 139495-73-1 tert-butyl 4-<5-cyclopropylamino)-2-fluoro-4-aminophenyl>-1-piperazinecarboxylate 
• 135861-05-1 4-<5-cyclopropylamino)-2-fluoro-4-nitrophenyl>piperazine 
• 135861-04-0 5-chloro-n-cyclopropyl-4-fluoro-2-nitroaniline 
• 578-28-9 1-Chloro-2,5-difluoro-4-nitrobenzene 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 137858-18-5 5-cyclopropyl-8-fluoro-2-hydroxy-7-(1-piperazinyl)-pyrimido[1,6-a]benzimidazole-1,3(2H,5H)-dione hydrochloride 

Relevant academic research and scientific papers

Amino substituted pyrimido[1,6-2]benzimidazoles

The present invention relates to novel substituted pyrimidobenzimidazole derivatives of the formula STR1 wherein the substituents are as described in the specification, and pharmaceutically acceptable salts thereof. The products have an inhibitory action

Pyrimido[1,6-a]benzimidazoles: A new class of DNA gyrase inhibitors

Substituted 4-quinolone- (1, A = CH) and 1,8-naphthyrid-4-one- (1, A = N) 3-carboxylic acids are currently the only classes of clinically useful antibacterial agents exerting their activity by inhibiting the subunit A of DNA gyrase. Pyrimido[1,6-a]benzimi