137939-47-0

Upstream product

• 81481-22-3 (20S)-20-methyl-5,16-pregnadien-1α,3β,21-triol 1,3-diacetate 
• 66875-21-6 (20S)-(20-Methyl-5-pregnen-1α,3β,21-triol)-1α,3β-diacetat 
• 77308-29-3 (17Z)-5,17-pregnadiene-1α,3β-diol diacetate 
• 140221-99-4 1α,3β-bis<(tert-butyldimethylsilyl)oxy>-23,24-bisnorchol-5-en-22-ol 
• 66875-19-2 (20S)-20-Methyl-21-(tetrahydro-2H-pyran-2-yl)oxy-5-pregnen-1α,3β-diol 
• 140222-02-2 1α,3β-bis(tert-butyldimethylsilyloxy)-23-oxa-5,7-cholestadien-25-ol 
• 114694-12-1 (S)-2-{(R)-4-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(E)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-propan-1-ol 
• 75-16-1 methylmagnesium bromide 
• 137832-47-4 ((S)-2-{(R)-4-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(E)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-propoxy)-acetic acid tert-butyl ester 
• 137832-48-5 1-((S)-2-{(R)-4-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(E)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-propoxy)-2-methyl-propan-2-ol 
• 140221-98-3 (20S)-20-methyl-1α,3β-bis(tert-butyldimethylsilyloxy)-21-(tetrahydropyran-2-yl)oxy-5-pregnene 
• 140222-01-1 (20S)-20-methyl-1α,3β-bis(tert-butyldimethylsilyloxy)-5,7-pregnadien-21-ol acetate 
• 66875-20-5 (20S)-(20-Methyl-21-(tetrahydro-2H-pyran-2-yl)oxy-5-pregnen-1α,3β-diol)-diacetat 
• 140222-00-0 (20S)-20-methyl-1α,3β-bis(tert-butyldimethylsilyloxy)-5-pregnen-21-ol acetate 

Downstream Products

• 87407-63-4 23-Oxa-calcitriol 
• 137832-48-5 1-((S)-2-{(R)-4-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-propoxy)-2-methyl-propan-2-ol 
• 140387-52-6 23-oxa-1α,25-dihydroxyvitamin D₃ 

Relevant academic research and scientific papers

Synthesis of 23-oxa-calcitriol derivatives

A convenient synthetic strategy leading to 23-oxa-calcitriol and 23-oxa-10,19-methylene-calcitriol is disclosed.

Synthetic studies of vitamin D analogues. IX. Synthesis and differentiation-inducing activity of 1α,25-dihydroxy-23-oxa-, thia-, and azavitamin D3

Three vitamin D3 analogues, 1α,25-dihydroxy-23-oxavitamin D3 (3), 1α,25-dihydroxy-23-thiavitamin D3 (4) and 1α,25-dihydroxy-23-azavitamin D3 (5) were synthesized. In the differentiation-inducing activity of huma