1379596-17-4Relevant articles and documents
An approach to the site-selective deoxygenation of hydroxy groups based on catalytic phosphoramidite transfer
Jordan, Peter A.,Miller, Scott J.
, p. 2907 - 2911 (2012)
Selective: The deoxygenation of simple and complex natural products employing a readily synthesized phosphoramidite and tetrazole catalysts can be executed as a two-step process, without the need to isolate intermediate deoxygenation precursors. Furthermore, a peptide-based tetrazole catalyst controls the site selectivity of deoxyerythromycin synthesis (see scheme), thus overcoming the notorious challenges with unprotected erythromycin A. Copyright