137961-52-5

Basic information

• Product Name: Phenol, 4,4'-[5,5'-bi-1H-benzimidazole]-2,2'-diylbis-
• CAS NO: 137961-52-5
• Molecular Formula: C26H18N4O2
• Molecular Weight: 418.455
• Mol File: 137961-52-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Phenol, 4,4'-[5,5'-bi-1H-benzimidazole]-2,2'-diylbis-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4,4'-[5,5'-bi-1H-benzimidazole]-2,2'-diylbis-(137961-52-5)
• EPA Substance Registry System: Phenol, 4,4'-[5,5'-bi-1H-benzimidazole]-2,2'-diylbis-(137961-52-5)

Safety Data

• Hazardous Substances Data: 137961-52-5(Hazardous Substances Data)

Upstream product

• 91-95-2 3,3',4,4'-tetraaminobiphenyl 
• 123-08-0 4-hydroxy-benzaldehyde 
• 7411-49-6 3,3',4,4'-tetraaminobiphenyl tetrahydrochloride dihydrate 
• 54998-28-6 ethyl 4-hydroxybenzenecarboximidoate hydrochloride 
• 17696-62-7 Phenyl 4-hydroxybenzoate 

Relevant articles and documents

Strong, specific, reversible binding ligands for transfer RNA: Comparison by fluorescence and NMR spectroscopies with distamycin binding for a new structural class of ligand

Binding data are presented for the interaction with brewer's yeast tRNA(Phe) of a new structural family of ligands, symmetrical bis- benzimidazoles. In addition specific perturbations in chemical shifts were detected by 1-dimensional NMR spectroscopy at 400 MHz for some imino and aromatic methyl protons of tRNA(Phe) when the tRNA was titrated with distamycin. Competitive displacement of the benzimidazole by added distamycin was followed fluorescence spectroscopy.

ANTIBACTERIAL COMPOUNDS

Disclosed are compounds of formula (I), which are of use in the treatment of bacterial diseases and infections, to compositions containing those compounds and to methods of treating bacterial diseases and infections using the compounds. In particular, the compounds are useful for the treatment of infection with, and diseases caused by, Clostridium difficile.

New developments in thermally stable polymers

Advances in high-temperature polymers since 1985 are discussed with the emphasis on the chemistry.High-temperature polymers refer to materials that exhibit glass-transition temperatures > 200 deg C and have the chemical structure expected to provide high thermooxidative stability.Specific polymers or series of polymers were selected to show how the chemical structure influences certain properties.Poly(arylene ethers) and polyimides are the two principal families of polymers discussed.Recent work on poly(arylene ethers) has concentrated on incorporating heterocyclic units within the polymer backbone.Recent polyimide work has centered on the synthesis of new polymers from novel monomers, several containing the trifluoromethyl group strategically located on the molecule.Various members in each of these polymer families display a unique combination of properties, heretofore unattainable.Other families of polymers are also briefly discussed with a polymer from an AB maleimidobenzocyclobutene exhibiting an especially attractive combination of properties.