1379671-49-4Relevant academic research and scientific papers
Cu/Pd-catalyzed, three-component click reaction of azide, alkyne, and aryl halide: One-pot strategy toward trisubstituted triazoles
Wei, Fang,Li, Haoyu,Song, Chuanling,Ma, Yudao,Zhou, Ling,Tung, Chen-Ho,Xu, Zhenghu
, p. 2860 - 2863 (2015)
A Cu/Pd-catalyzed, three-component click reaction of azide, alkyne, and aryl halide has been developed. By using this Cu/Pd transmetalation relay catalysis, a variety of 1,4,5-trisubstituted 1,2,3-triazoles were quickly assembled in one step in high yield
Palladium-Catalyzed Regioselective C-5 Arylation of 1,2,3-Triazoles with Diaryliodonium Salts
Gang, Fangli,Che, Yang,Du, Zhengyin,Feng, Hua,Fu, Ying
supporting information, p. 1624 - 1629 (2017/08/11)
An effective method for C-5 arylation of 1,4-disubstituted 1,2,3-triazoles and C-5 regioselective arylation of 1-substituted 1,2,3-triazoles via sp 2 C-H activation with palladium as a catalyst and diaryliodonium salts as arylating reagents is described. Various electron-rich and electron-deficient substituents attached to triazoles and diaryliodonium salts were tolerable to give the desired products with good isolated yields in 24 hours under air atmosphere.
Pd-NHC-catalyzed direct arylation of 1,4-disubstituted 1,2,3-triazoles with aryl halides
He, Tao,Wang, Min,Li, Pinhua,Wang, Lei
experimental part, p. 979 - 984 (2012/06/01)
A highly efficient method for the synthesis of unsymmetrical multi-substituted 1,2,3-triazoles via a direct Pd-NHC system catalyzed C(5)-arylation of 1,4-disubstituted triazoles, which are readily accessible via "click" chemistry has been developed. It is
