1379680-87-1

Upstream product

• 1453867-95-2 (S)-4-((4-methoxybenzyl)oxy)pent-1-en-3-one 
• 861902-93-4 (S)-N-methoxy-2-((4-methoxybenzyl)oxy)-N-methylpropanamide 
• 229647-61-4 (S)-2-((4-methoxybenzyl)oxy)propanoic acid 
• 824-94-2 p-methoxybenzyl chloride 
• 144401-98-9 (S)-2-(4-methoxybenzyloxy)propionic acid ethyl ester 
• 1826-67-1 vinyl magnesium bromide 
• 126361-27-1 (S)-(p-methoxybenzyloxy)propanal 
• 205934-53-8 (3aR,5R,6R,6aR)-6-(4-methoxybenzyloxy)-2,2-dimethyl-5-vinyltetrahydrofuro[2,3-d][1,3]dioxole 
• 69940-02-9 3-O-(4-Methoxybenzyl)-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 
• 69940-04-1 (R)-1-[(3aR,5R,6R,6aR)-6-(4-methoxybenzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol 
• 1379680-89-3 (2S,3R)-2-(4-methoxybenzyloxy)pent-4-ene-1,3-diol 
• 1379680-88-2 (3R,4R)-4-(4-methoxybenzyloxy)-5-oxopent-1-en-3-yl formate 

Downstream Products

• 1379680-91-7 (3R,4S)-4-(4-methoxybenzyloxy)pent-1-en-3-yl (3R)-3-(tert-butyldimethylsilyloxy)butanoate 
• 1379680-93-9 C₁₉H₃₄O₅Si 
• 1379680-97-3 C₂₉H₄₂O₇SSi 
• 1379680-86-0 2-tosylethyl (4R,5S,E)-4-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)hex-2-enoate 
• 1379680-83-7 (2R)-4-[(3R,4S)-4-(4-methoxybenzyloxy)pent-1-en-3-yloxy]-4-oxobutan-2-yl (4R,5S,E)-5-(acryloyloxy)-4-(tert-butyldimethylsilyloxy)hex-2-enoate 
• 1379680-85-9 (3R,4S)-4-(4-methoxybenzyloxy)pent-1-en-3-yl (3R)-3-hydroxybutanoate 
• 1379680-92-8 tert-butyl-[(3R,4S)-4-(4-methoxybenzyloxy)pent-1-en-3-yloxy]dimethylsilane 

Relevant academic research and scientific papers

Stereoselective synthesis of macrosphelide i

An efficient total synthesis of macrosphelide I, has been achieved starting from commercially available chiral materials, ethyl (S)-lactate and methyl (R)-3-hydroxybutyrate. Titanium(IV) promoted the regioselective nucleophilic opening reaction of epoxy a

A Convergent Synthetic Strategy towards Oligosaccharides containing 2,3,6-Trideoxypyranoglycosides

A de novo synthetic strategy for the production of oligosaccharides containing 2,3,6-trideoxypyranoglycoside is reported. The key event is the Pd-catalyzed asymmetric diastereoselective hydroalkoxylation of ene-alkoxyallene-linked glycosidic fragments. The utility of this approach was demonstrated by the activation-free, stereodivergent, and convergent synthesis of various 2-deoxyoligosaccharides, as well as their aglycon conjugates.

De novo synthesis of novel bacterial monosaccharide fusaminic acid

Fusobacterium nucleatum is an oral bacteria related to various types of diseases. As Gram-negative bacteria, lipopolysaccharide (LPS) of Fusobacterium nucleatum could be a potential virulence factor. Recently, the structure of O-antigen in LPS of Fusobact

Total synthesis of macrosphelide M from diacetone glucose

The total synthesis of macrosphelide M is described. The key steps include the preparation of the acid and alcohol fragments from diacetone glucose and (S)-malic acid, respectively, followed by Yamaguchi esterification and macrocyclization of the tris-olefin by ring-closing metathesis. Finally, one-pot deprotection of the PMB and TBS groups with TiCl4 results in the target. The C-3/C-4 stereocenters of diacetone glucose are used for the introduction of four stereocenters, whereas the fifth stereocenter is realized from (S)-malic acid. The total synthesis of macrosphelide M was achieved from diacetone glucose and (S)-malic acid. The key steps include Yamaguchi esterification and macrocyclization of the tris-olefin by the second-generation Grubbs catalyst.