1379771-66-0

Basic information

• Product Name: tert-butyl 1-(2-(benzyloxy)-2-((3aR,5R,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydro-furo[2,3-d][1,3]dioxol-5-yl)ethylamino)-3-methyl-1-oxobutan-2-ylcarbamate
• CAS NO: 1379771-66-0
• Molecular Weight: 598.737
• Mol File: 1379771-66-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 1-(2-(benzyloxy)-2-((3aR,5R,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydro-furo[2,3-d][1,3]dioxol-5-yl)ethylamino)-3-methyl-1-oxobutan-2-ylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 1-(2-(benzyloxy)-2-((3aR,5R,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydro-furo[2,3-d][1,3]dioxol-5-yl)ethylamino)-3-methyl-1-oxobutan-2-ylcarbamate(1379771-66-0)
• EPA Substance Registry System: tert-butyl 1-(2-(benzyloxy)-2-((3aR,5R,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydro-furo[2,3-d][1,3]dioxol-5-yl)ethylamino)-3-methyl-1-oxobutan-2-ylcarbamate(1379771-66-0)

Safety Data

• Hazardous Substances Data: 1379771-66-0(Hazardous Substances Data)

Upstream product

• 2280-44-6 D-Glucose 
• 2847-00-9 1,2:5,6-di-O-isopropylidene-α-D-hexofuran-3-ulose 
• 26275-20-7 1,2-O-isopropylidene-6-O-p-toluenesulfonyl-α-D-allofuranose 
• 2595-05-3 Diacetone D-glucose 
• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 

Relevant articles and documents

Sugar-amino acid cyclic conjugates as novel conformationally constrained hydroxyethylamine transition-state isosteres

Hydroxyethylamine (HEA) isosteres have previously been shown to display a multitude of biomedical applications. In fact, the first protease inhibitor, saquinavir is an HEA based peptidomimetic. Herein we describe an easy-to-operate synthetic route to a series of carbohydrate-based conformationally constrained hydroxyethylamine (HEA) isosteres featuring amino acid side chains, starting from d-glucose. This class of novel sugar-amino acid-tethered conformationally restricted HEA systems may have bearing in practical application, particularly in the development of conformationally restricted protease inhibitors.