26275-20-7Relevant articles and documents
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Szabolcs,Prey
, p. 1112,1114 (1957)
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Synthesis, characterization, and antimicrobial activities of novel monosaccharide-containing Schiff base ligands
?etin Telli, Fatma,Astley, Stephen Thomas,Salman, Azize Ye?im
, p. 370 - 380 (2017/07/04)
Four new chiral Schiff base ligands (3a–4a, 3b–4b) have been prepared using aminoisopropylidene derivatives of glucose and aminochloralose derivatives of mannose. The synthesized compounds 1 and 2 were characterized by nuclear magnetic resonance (1/
Synthesis of [18F]-6-deoxy-6-fluoro-D-glucose ([ 18F]6FDG), a potential tracer of glucose transport
Neal, Timothy R.,Schumann, William C.,Berridge, Marc S.,Landau, Bernard R.
, p. 845 - 854 (2007/10/03)
With the goal of developing a PET radioligand for the in vivo assessment of glucose transport, 6-deoxy-6-[18F]fluoro-D-glucose ([ 18F]6FDG) was prepared in two steps from 18F-. Starting with D-glucose, the tosyl- and mesyl-derivatives of 3,5-O-benzylidene-1,2-O-isopropylidene-α-D-glucofuranose were prepared by known methods. Reaction of either of these precursors with 18F - resulted in the formation of 3,5-O-benzylidene-6-deoxy-O-[ 18F]-fluoro-1,2-O-isopropylidene-α-D-glucofuranose in high yield. Subsequent hydrolysis resulted in the production of [18F]6FDG. Under optimal conditions, [18F]6FDG is produced 60-70 min after end of bombardment (EOB) in 71 ± 12% yield (decay corrected, based upon fluoride) with a radiochemical purity of ≥96%. Preliminary experiments have indicated that [18F]6FDG may be a more representative in vivo tracer for the glucose transporter than 2FDG. Copyright