1379773-01-9Relevant academic research and scientific papers
Copper-catalyzed cross-coupling interrupted by an opportunistic smiles rearrangement: An efficient domino approach to dibenzoxazepinones
Kitching, Matthew O.,Hurst, Timothy E.,Snieckus, Victor
supporting information; experimental part, p. 2925 - 2929 (2012/05/04)
Unexpected Smiles! An unusual and highly regioselective synthesis of dibenzoxazepinones by a domino sequence assisted by an unexpected Smiles rearrangement is reported. The process is effective on electronically differentiated phenols and shows a high tolerance to variation in the benzamide substituents. A plausible path for the reaction, supported by preliminary mechanistic data, is offered. Copyright
