1379793-72-2

Basic information

• Product Name: 1-(4'-methylthiophenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene
• Synonyms: 1-(4'-methylthiophenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene
• CAS NO: 1379793-72-2
• Molecular Weight: 316.421
• Mol File: 1379793-72-2.mol

Chemical Properties

• CAS DataBase Reference: 1-(4'-methylthiophenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4'-methylthiophenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene(1379793-72-2)
• EPA Substance Registry System: 1-(4'-methylthiophenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene(1379793-72-2)

Safety Data

• Hazardous Substances Data: 1379793-72-2(Hazardous Substances Data)

Upstream product

• 35371-03-0 4-iodothioanisole 
• 77295-62-6 1,1-Dibromo-2-(3',4',5'-trimethoxyphenyl)ethene 
• 53560-33-1 3,4,5-trimethoxyphenylacetylene 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 1136-86-3 methyl (3,4,5-trimethoxyphenyl) ketone 
• 359784-71-7 C₁₁H₁₆N₂O₃ 
• 18620-04-7 4-thioanisolemagnesium bromide 

Relevant articles and documents

Negishi cross-coupling reaction as a route to isocombretastatins

A series of isocombretastatins A has been synthesized by a new method based on the Negishi cross-coupling reaction in 19-84% yields. Five of the synthesized compounds exhibit high cytotoxic activity in nanomolar concentrations (IC50 = 1-100 n) towards Jurkat, K562, Colo357, and A549 cell lines. Georg Thieme Verlag Stuttgart · New York.

Synthesis of 1,1-diarylethylenes via efficient iron/copper Co-catalyzed coupling of 1-arylvinyl halides with Grignard reagents

An efficient access to 1,1-diarylethylenes of biological interest by coupling functionalized aryl Grignard reagents and 1-arylvinyl halides in the presence of FeCl3/CuTC is described. This bimetallic system proved to be superior to the use of Fe or Cu catalyst alone. The synthetic utility of this protocol is illustrated in the field of steroid chemistry.