359784-71-7Relevant academic research and scientific papers
Lewis acid-promoted direct synthesis of N-unsubstituted hydrazones via the reaction of hydrazine with acetophenone and isatin derivatives
El-Azab,Ghabbour,El-Husseiny,Maarouf,Mohamed,Abdel-Aziz
, p. 2837 - 2844 (2017/03/22)
Hydrazones 2–22 were synthesized via the reaction of acetophenone with isatin derivatives and anhydrous hydrazine promoted by BF3 as a Lewis acid at 0°C. Structures of the synthesized hydrazones were determined on the basis of NMR and X-ray crystallograph
Synthesis of 1,1-diarylethylenes via efficient iron/copper Co-catalyzed coupling of 1-arylvinyl halides with Grignard reagents
Hamze, Abdallah,Brion, Jean-Daniel,Alami, Mouad
supporting information; scheme or table, p. 2782 - 2785 (2012/07/14)
An efficient access to 1,1-diarylethylenes of biological interest by coupling functionalized aryl Grignard reagents and 1-arylvinyl halides in the presence of FeCl3/CuTC is described. This bimetallic system proved to be superior to the use of Fe or Cu catalyst alone. The synthetic utility of this protocol is illustrated in the field of steroid chemistry.
