1379793-80-2Relevant academic research and scientific papers
Synthesis of 1,1-diarylethylenes via efficient iron/copper Co-catalyzed coupling of 1-arylvinyl halides with Grignard reagents
Hamze, Abdallah,Brion, Jean-Daniel,Alami, Mouad
, p. 2782 - 2785 (2012/07/14)
An efficient access to 1,1-diarylethylenes of biological interest by coupling functionalized aryl Grignard reagents and 1-arylvinyl halides in the presence of FeCl3/CuTC is described. This bimetallic system proved to be superior to the use of Fe or Cu catalyst alone. The synthetic utility of this protocol is illustrated in the field of steroid chemistry.
