1380167-27-0Relevant articles and documents
Synthesis and binding properties of new selective ligands for the nucleobase opposite the AP site
Abe, Yukiko,Nakagawa, Osamu,Yamaguchi, Rie,Sasaki, Shigeki
, p. 3470 - 3479 (2012/08/08)
DNA is continuously damaged by endogenous and exogenous factors such as oxidative stress or DNA alkylating agents. These damaged nucleobases are removed by DNA N-glycosylase and form apurinic/apyrimidinic sites (AP sites) as intermediates in the base exci